Calcified Tissue International

, Volume 52, Issue 4, pp 278–282

Distribution of fluoride in cortical bone of human rib

Authors

  • Koji Ishiguro
    • Department of Preventive Dentistry and Dental Public Health, School of DentistryAichi-Gakuin University
  • Haruo Nakagaki
    • Department of Preventive Dentistry and Dental Public Health, School of DentistryAichi-Gakuin University
  • Shinji Tsuboi
    • Department of Preventive Dentistry and Dental Public Health, School of DentistryAichi-Gakuin University
  • Naoki Narita
    • Department of Preventive Dentistry and Dental Public Health, School of DentistryAichi-Gakuin University
  • Kazuo Kato
    • Department of Preventive Dentistry and Dental Public Health, School of DentistryAichi-Gakuin University
  • Jianxue Li
    • Department of Preventive Dentistry and Dental Public Health, School of DentistryAichi-Gakuin University
  • Hideo Kamei
    • Department of Surgery, School of DentistryAichi-Gakuin University
  • Ikuo Yoshioka
    • Division of General EducationAichi-Gakuin University
  • Kenichi Miyauchi
    • Division of General EducationAichi-Gakuin University
  • Hiroyo Hosoe
    • Division of General EducationAichi-Gakuin University
  • Ryouyu Shimano
    • Division of General EducationAichi-Gakuin University
  • John A. Weatherell
    • Department of Oral Biology, School of DentistryUniversity of Leeds
  • Colin Robinson
    • Department of Oral Biology, School of DentistryUniversity of Leeds
Clinical Investigations

DOI: 10.1007/BF00296652

Cite this article as:
Ishiguro, K., Nakagaki, H., Tsuboi, S. et al. Calcif Tissue Int (1993) 52: 278. doi:10.1007/BF00296652

Summary

We describe a detailed study of fluoride distribution with age in the human cortical rib bone. Human ribs were obtained from 110 subjects (M:68,F;42) aged 20–93 years. The fluoride distribution from the periosteal to endosteal surfaces of the ribs was determined by sampling each specimen using an abrasive micro-sampling technique, and the samples were analyzed using the fluoride electrode, as described by Weatherell et al. [1]. The concentration of fluoride was highest in the periosteal region, decreased gradually towards the interior of the tissue where the concentration of fluoride tended toward the plateau, and then rose again towards the endosteal surface. Patterns of fluoride distribution changed with age, and the difference between periosteal and endosteal fluoride levels increased with age. Although average fluoride concentrations increased with age in both sexes, there was a significant difference between males and females at the age of about 55 years (P<0.05).

Key words

FluorideBoneHumanAgingSex

Copyright information

© Springer-Verlag New York Inc 1993