Current Microbiology

, Volume 31, Issue 1, pp 23–27

Bifidobacteria and probiotic effects: Action of Bifidobacterium species on conjugated bile salts

  • J. P. Grill
  • C. Manginot-Dürr
  • F. Schneider
  • J. Ballongue
Article

DOI: 10.1007/BF00294629

Cite this article as:
Grill, J.P., Manginot-Dürr, C., Schneider, F. et al. Current Microbiology (1995) 31: 23. doi:10.1007/BF00294629

Abstract

The effect of six different conjugated bile salts (two trihydroxyconjugated bile salts: tauro and glycocholic acids; and four dihydroxyconjugated bile salts: tauro- and glycochenodeoxycholic, tauro- and glycodeoxycholic acids) on eight bifidobacteria strains were studied. A strong growth-inhibitory effect was observed (80% at 0.95mm) for each bile salt and strain. This phenomenon was explained by the production of deconjugated bile salt during bifidobacteria growth. The deconjugation phenomenon was concurrent with biomass production, and deconjugated bile salts were the sole compound produced during bifidobacteria biotransformation. In resting cell experiments, differences appeared between the strains and the kind of bile salts, particularly concerning taurocholic acid. The Bifidobacterium longum strains were the most efficient among the bacteria tested.

Copyright information

© Springer-Verlag New York Inc 1995

Authors and Affiliations

  • J. P. Grill
    • 1
  • C. Manginot-Dürr
    • 1
  • F. Schneider
    • 1
  • J. Ballongue
    • 1
  1. 1.Institut Henry Tissier, Laboratoire de Chimie Biologique IUniversité de Nancy IVandoeuvre lès NancyFrance