Chromosoma

, Volume 95, Issue 5, pp 350–358

High resolution G-banded chromosomes of the mouse

  • Jeffrey R. Sawyer
  • Martha M. Moore
  • John C. Hozier
Article

DOI: 10.1007/BF00293182

Cite this article as:
Sawyer, J.R., Moore, M.M. & Hozier, J.C. Chromosoma (1987) 95: 350. doi:10.1007/BF00293182
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Abstract

High resolution G-banded mouse chromosomes were prepared using an actinomycin D and acridine orange pretreatment protocol, resulting in late prophase mouse chromosomes which reveal over twice the number of bands as compared with mid metaphase. These elongated chromosomes, described here in detail and used to construct a precise schematic representation of the late prophase banding patterns, should be generally useful in high resolution mouse chromosome analysis.

Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • Jeffrey R. Sawyer
    • 1
  • Martha M. Moore
    • 2
  • John C. Hozier
    • 1
  1. 1.Medical Genetics Laboratory, Department of Biological SciencesFlorida Institute of TechnologyMelbourneUSA
  2. 2.Mutagenesis and Cellular Toxicology Branch, Genetic Toxicology DivisionU.S. Environmental Protection AgencyResearch Triangle ParkUSA
  3. 3.Clinical and Diagnostic FoundationGenetics Center Driscoll Children's HospitalCorpus ChristiUSA
  4. 4.Institute of Molecular Biophysics and Department of Biological ScienceFlorida State UniversityTallahasseeUSA