, Volume 89, Issue 4, pp 294-320

First online:

A photographic representation of the variability in the G-banded structure of the chromosomes in the mouse karyotype

A guide to the identification of the individual chromosomes
  • John K. CowellAffiliated withDepartment of Hematology and Oncology, Laboratory of Molecular Genetics, Institute for Child Health

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Analysis of the mouse chromosomes is becoming increasingly important in many fields of genetic research. It is generally considered that the mouse chromosomes are more difficult to analyse than, for example, human chromosomes which has often led to their misidentification. This article presents a guide to the correct identification of trypsin-Giemsa banded chromosomes from the mouse. The variability in the G-banded structure of each chromosome is presented pictorially together with some suggestions for their unequivocal identification. Since many of the mouse chromosomes have similar banding patterns, those chromosomes which are more frequently misidentified have been compared and contrasted. Finally a summary of the main features for the identification of each chromosome is presented.