Human Genetics

, Volume 67, Issue 4, pp 455–456

Del11p13/nephroblastoma without aniridia

Authors

  • Catherine Turleau
    • ER. 149 C.N.R.S.Hôpital Necker-Enfants-Malades 149
    • U. 173 I.N.S.E.R.M.Hôpital Necker-Enfants-Malades 149
  • J. de Grouchy
    • ER. 149 C.N.R.S.Hôpital Necker-Enfants-Malades 149
    • U. 173 I.N.S.E.R.M.Hôpital Necker-Enfants-Malades 149
  • Claire Nihoul-Fékété
    • Clinique Chirurgicale InfantileHôpital Necker-Enfants-Malades
  • J. L. Dufier
    • Service d'OphtalmologieHôpital Necker-Enfants-Malades
  • Françoise Chavin-Colin
    • ER. 149 C.N.R.S.Hôpital Necker-Enfants-Malades 149
    • U. 173 I.N.S.E.R.M.Hôpital Necker-Enfants-Malades 149
  • Claudine Junien
    • Institut de Pathologie MoléculaireC.H.U. Cochin
Clinical Case Reports

DOI: 10.1007/BF00291410

Cite this article as:
Turleau, C., de Grouchy, J., Nihoul-Fékété, C. et al. Hum Genet (1984) 67: 455. doi:10.1007/BF00291410

Summary

A patient is reported with del11p13, low catalase level, nephroblastoma, chordee and cryptorchidism, no evident mental retardation, and with normal irides. This unique observation suggests the following order of loci in 11p13, from centromere to telomere: catalase, Wilms tumor, aniridia. The chromosomal origin of nephroblastoma may be more frequent than estimated on the basis of its association with aniridia.

Copyright information

© Springer-Verlag 1984