Human Genetics

, Volume 66, Issue 4, pp 289–291

Diagnostic insonation of extra utero human placentas: No effect of lymphocytic sister chromatid exchange

  • A. Brulfert
  • V. Ciaravino
  • M. W. Miller
  • D. Maulik
  • E. L. Carstensen
Original Inverstigations

DOI: 10.1007/BF00287629

Cite this article as:
Brulfert, A., Ciaravino, V., Miller, M.W. et al. Hum Genet (1984) 66: 289. doi:10.1007/BF00287629

Summary

Freshly delivered human placentas were exposed to ultrasound for 30 min using a diagnostic linear array unit. Blood was then drawn and cultured in the presence of bromodeoxyuridine, and the frequencies of sister chromatid exchanges (SCE) in the lymphocytes determined. There was no statistically significant difference in SCE frequencies between control and exposed cells; the frequencies of SCEs per cell ranged from 4.50 to 6.02 for control and from 4.66 to 6.10 for exposed cells in five separate experiments. Positive control mitomycin C treated cells were significantly affected, with more than 50 SCEs per cell.

Copyright information

© Springer-Verlag 1984

Authors and Affiliations

  • A. Brulfert
    • 1
  • V. Ciaravino
    • 2
  • M. W. Miller
    • 2
  • D. Maulik
    • 3
  • E. L. Carstensen
    • 4
  1. 1.Laboratorire de Biologie CellulaireFaculté des Sciences Pharmaceutiques et BiologiguesParis Cedex 06France
  2. 2.Department of Radiation Biology and BiophysicsThe University of RochesterRochesterUSA
  3. 3.Department of Obstetrics and GynecologyThe University of RochesterRochesterUSA
  4. 4.Department of Electrical EngineeringThe University of RochesterRochesterUSA