Human Genetics

, Volume 75, Issue 4, pp 345–349

Fragile sites, chromosome evolution, and human neoplasia

Authors

  • Rosa Miró
    • Departament de Biologia Cel.lular i FisiologiaUniversitat Autònoma de Barcelona
    • Institut de Biologia Fonamental “Vincent Villar Palasí”Universitat Autònoma de Barcelona
  • Inmaculada Concepción Clemente
    • Departament de Biologia Cel.lular i FisiologiaUniversitat Autònoma de Barcelona
  • Carmen Fuster
    • Departament de Biologia Cel.lular i FisiologiaUniversitat Autònoma de Barcelona
  • José Egozcue
    • Departament de Biologia Cel.lular i FisiologiaUniversitat Autònoma de Barcelona
    • Institut de Biologia Fonamental “Vincent Villar Palasí”Universitat Autònoma de Barcelona
Original Investigations

DOI: 10.1007/BF00284105

Cite this article as:
Miró, R., Clemente, I.C., Fuster, C. et al. Hum Genet (1987) 75: 345. doi:10.1007/BF00284105

Summary

In a study of the possible relationship between human fragile sites, chromosomal rearrangements related to neoplasia, and chromosome regions involved in evolutionary changes, we have found that 17 fragile sites related to cancer, 15 fragile sites not related to cancer, and 17 non-fragile regions also related to human malignancy correspond or are close to bands involved in rearrangements that have taken place during chromosomal evolution in primates.

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Copyright information

© Springer-Verlag 1987