Human Genetics

, Volume 57, Issue 2, pp 138–141

The genes for growth hormone and chorionic somatomammotropin are on the long arm of human chromosome 17 in region q21→qter

Authors

  • Donna L. George
    • Department of MedicineThe Howard Hughes Medical Institute Laboratory for Human Biochemical Genetics
  • John A. PhillipsIII
    • Department of PediatricsThe Johns Hopkins School of Medicine
  • Uta Francke
    • Department of Human GeneticsYale University School of Medicine
  • Peter H. Seeburg
    • Department of Molecular BiologyGenentech, Inc.
Original Investigations

DOI: 10.1007/BF00282009

Cite this article as:
George, D.L., Phillips, J.A., Francke, U. et al. Hum Genet (1981) 57: 138. doi:10.1007/BF00282009

Summary

We used a cloned cDNA probe for human growth hormone and Southern blotting techniques to analyze DNA from a series of rodentxhuman somatic cell hybrids for the presence of growth hormone-related sequences. Our results provide evidence for the assignment of the genes for growth hormone and chorionic somatomammotropin as well as a growth hormone-like gene to human chromosome 17. Analysis of mousexhuman hybrid cells containing only part of the long arm of chromosome 17 enabled us to localize these genes to region 17q21→17qter.

Copyright information

© Springer-Verlag 1981