Journal of Mathematical Biology

, Volume 4, Issue 1, pp 1–20

Effect of the rate of oxygen consumption on muscle respiration

  • B. A. Taylor
  • J. D. Murray

DOI: 10.1007/BF00276348

Cite this article as:
Taylor, B.A. & Murray, J.D. J. Math. Biology (1977) 4: 1. doi:10.1007/BF00276348


An important role of myoglobin in red muscle is to facilitate the diffusion of oxygen for metabolism. We consider a model for muscle respiration in which the oxygen consumption is of a MichaelisMenten form. The resulting mathematical model is solved in two different ways with two different boundary conditions. The first uses the singular perturbation method of Murray (1974), while the second, which gives another justication of the simpler procedure, is a direct numerical computation of the full problem.

The oxygen tension and saturation are often small. For realistic values of the Michaelis-Menten constant the oxygen tension, the saturation and the radius of the region in which the oxygen tension is negligibly small can be calculated using the constant consumption model of Murray (1974), with corrected boundary conditions (those for a Stefan problem), which in certain circumstances markedly affect the solution.

Copyright information

© Springer-Verlag 1977

Authors and Affiliations

  • B. A. Taylor
    • 1
  • J. D. Murray
    • 2
  1. 1.Oxford
  2. 2.Mathematical InstituteOxfordGreat Britain