Human Genetics

, Volume 77, Issue 2, pp 142–144

Localization of the human multiple drug resistance gene, MDR1, to 7q21.1

  • D. F. Callen
  • E. Baker
  • R. N. Simmers
  • R. Seshadri
  • I. B. Roninson
Original Investigations

DOI: 10.1007/BF00272381

Cite this article as:
Callen, D.F., Baker, E., Simmers, R.N. et al. Hum Genet (1987) 77: 142. doi:10.1007/BF00272381

Summary

Multiple drug resistance has been shown to be associated with amplification/increased expression of a gene designated MDR. The localization of one member of the MDR gene family, MDR1, to the long arm of chromosome 7 by in situ hybridization is reported.

Copyright information

© Springer-Verlag 1987

Authors and Affiliations

  • D. F. Callen
    • 1
  • E. Baker
    • 1
  • R. N. Simmers
    • 1
  • R. Seshadri
    • 2
  • I. B. Roninson
    • 3
  1. 1.Cytogenetics Unit, Department of HistopathologyAdelaide Children's HospitalNorth AdelaideAustralia
  2. 2.Department of HaematologyFlinders Medical CentreBedford ParkAustralia
  3. 3.Center for GeneticsUniversity of Illinois at ChicagoChicagoUSA