Biotechnology

Applied Microbiology and Biotechnology

, Volume 28, Issue 4, pp 335-339

Adsorbents for extractive bioconversion applied to the acetone-butanol fermentation

  • Lena NielsenAffiliated withDepartment of Biotechnology, Chemical Center, University of Lund
  • , Mats LarssonAffiliated withDepartment of Biotechnology, Chemical Center, University of Lund
  • , Olle HolstAffiliated withDepartment of Biotechnology, Chemical Center, University of Lund
  • , Bo MattiassonAffiliated withDepartment of Biotechnology, Chemical Center, University of Lund

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Summary

Four different polymeric resins were tested as adsorbents in extractive bioconversion applied to the fermentative production of acetone and butanol by Clostridium acetobutylicum. The polymers were tested for their ability to adsorb butanol from pure solutions, and fermentation broths. Furthermore, the effect on the fermentability of the media was tested. The pH was increased to prevent adsorption of intermediates such as acetic and butyric acids. Bonopore, the polymer giving the best adsorption pattern with no undesirable effects, was tested in repeated batch cultures with C. acetobutylicum.