Experimental Brain Research

, Volume 73, Issue 2, pp 354–356

Place aversion induced by the substance P analogue, dimethyl-C7, is not state dependent: implication of substance P in aversion

  • P. J. Elliott

DOI: 10.1007/BF00248227

Cite this article as:
Elliott, P.J. Exp Brain Res (1988) 73: 354. doi:10.1007/BF00248227


Intraventricular infusion of the stable substance P analogue, DiMethyl-C7, was found to produce aversion in a place conditioning paradigm. This effect was independent of state dependent learning since the place aversion was also seen when the subjects were tested under the influence of the drug. A role for substance P in aversion is discussed.

Key words

Substance PSubstance P agonistsDiMethyl-C7Place conditioning

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • P. J. Elliott
    • 1
  1. 1.Department of Experimental PsychologyCambridge UniversityCambridgeUK
  2. 2.Neuropharmacology DepartmentGlaxo Group Research Ltd.WareUK