Experimental Brain Research

, Volume 11, Issue 4, pp 376-386

First online:

Perseverative interference in monkeys following selective lesions of the inferior prefrontal convexity

  • Susan D. IversenAffiliated withPsychological Laboratory University of Cambridge
  • , Mortimer MishkinAffiliated withDept. of Health Education and Welfare, National Institute of Mental Health

Rent the article at a discount

Rent now

* Final gross prices may vary according to local VAT.

Get Access


Monkeys with lesions of the inferior frontal convexity were impaired relative to controls in retaining an auditory frequency differentiation (although subsequent thresholds were normal) and in learning object and spatial reversals. Performance was characterized by perseverative interference, a frontal symptom which now seems attributable to damage to the inferior convexity.

Key Words

Prefrontal cortex Ablation Supramodal deficit Perseverative interference