Experimental Brain Research

, Volume 11, Issue 4, pp 376–386

Perseverative interference in monkeys following selective lesions of the inferior prefrontal convexity

  • Susan D. Iversen
  • Mortimer Mishkin

DOI: 10.1007/BF00237911

Cite this article as:
Iversen, S.D. & Mishkin, M. Exp Brain Res (1970) 11: 376. doi:10.1007/BF00237911


Monkeys with lesions of the inferior frontal convexity were impaired relative to controls in retaining an auditory frequency differentiation (although subsequent thresholds were normal) and in learning object and spatial reversals. Performance was characterized by perseverative interference, a frontal symptom which now seems attributable to damage to the inferior convexity.

Key Words

Prefrontal cortex Ablation Supramodal deficit Perseverative interference 

Copyright information

© Springer-Verlag 1970

Authors and Affiliations

  • Susan D. Iversen
    • 1
  • Mortimer Mishkin
    • 2
  1. 1.Psychological Laboratory University of CambridgeCambridgeEngland
  2. 2.Dept. of Health Education and WelfareNational Institute of Mental HealthUSA

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