, Volume 11, Issue 4, pp 376-386

Perseverative interference in monkeys following selective lesions of the inferior prefrontal convexity

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Monkeys with lesions of the inferior frontal convexity were impaired relative to controls in retaining an auditory frequency differentiation (although subsequent thresholds were normal) and in learning object and spatial reversals. Performance was characterized by perseverative interference, a frontal symptom which now seems attributable to damage to the inferior convexity.

This work was performed while the senior author was a visiting scientist at NIMH, Bethesda supported by postdoctoral fellowships from the Federation of University Women and the Science Research Council. Portions of the paper were presented at the meetings of the Eastern Psychological Association, 1966. We thank H.E. Rosvold for his active encouragement of this research.