Experimental Brain Research

, Volume 62, Issue 1, pp 215–223

The proportion and size of GABA-immunoreactive neurons in the magnocellular and parvocellular layers of the lateral geniculate nucleus of the rhesus monkey

  • V. M. Montero
  • J. Zempel
Research Note

DOI: 10.1007/BF00237420

Cite this article as:
Montero, V.M. & Zempel, J. Exp Brain Res (1986) 62: 215. doi:10.1007/BF00237420


Neurons containing GABA-immunoreactivity in LGN of the macaque monkey were analyzed quantitatively in semithin (1 μm) sections. The percentage of GABA(+) cells per unit area of the sections was 26% in the magnocellular layers and 19% in the parvocellular layers. However, the percentage of GABA(+) cells in a unit volume of LGN, calculated by a stereological method that takes into account the observed difference in size of labeled and unlabeled somata, was 35% in the magnocellular layers and 25% in the parvocellular layers. GABA(+) somata in the magnocellular layers were significantly larger than those in the parvocellular layers. The possible role of GABAergic cells in inhibitory mechanisms of receptive fields of parvo- and magnocellular neurons are discussed in the light of current knowledge of the physiology and neural circuits of macaque LGN.

Key words

Dorsal lateral geniculate nucleus GABA Inhibition Interneurons Immunocytochemistry 

Copyright information

© Springer-Verlag 1986

Authors and Affiliations

  • V. M. Montero
    • 1
  • J. Zempel
    • 1
  1. 1.Department of NeurophysiologyWaisman Center, University of WisconsinMadisonUSA