The human interleukin-6 receptor α chain gene is localized on chromosome 1 band q21
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- Kluck, P.M.C., Wiegant, J., Jansen, R.P.M. et al. Hum Genet (1993) 90: 542. doi:10.1007/BF00217455
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The human interleukin-6 receptor α chain (IL6Rα) gene was regionally mapped to chromosome 1 bridization probes, partially overlapping lambda clones encompassing 28 kb of the genomic region of the gene were used. These clones were isolated using a polymerase chain reaction (PCR)-generated fragment of the 3′ noncoding region of the gene. This localization confirms and extends the provisional assignment of the IL6Rα gene to chromosome 1, for which a panel of somatic cell hybrids was used.