Duct ectasia due to mucus-producing cancers with intraductal extension: histopathologic correlation with radiologic imagings
Purchase on Springer.com
$39.95 / €34.95 / £29.95*
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.
Although duct ectasia due to mucus-producing pancreatic cancer has been well known, its occurrence in other organs has not been reported. We have studied the pathologic basis of the radiologic features in cases of mucus-producing cancer with intraductal extension.
We conducted a comparative study of detailed various radiographic images and pathological findings in 10 cases of mucus-producing cancers (four of mucusproducing pancreatic cancer, two of mucinous gastric cancer with diffuse lymphangitic liver metastasis, and four cases of bronchoalveolar cell carcinoma with cyst or cavity).
When mucus-producing cancer occurs in a secretory duct or extends into lymphatic ducts, the normal duct is dilated due to the mucus and increased internal pressure, leading to the formation of a cyst and cavity. Because of having the liquid property of mucus floating cancer cells, the lesion can easily progress to continuous ducts as well as regionally.
In cases of mucus-producing cancer with extension into the ductal structure not only in the pancreas but also in the lung and liver, continuous duct ectasis and cysts filled with mucus or cavities of all sizes made by the nature of the mucus may be detected by CT and US.
- Robbins SL, Cotran RS. Pathologic basis of disease, 2nd ed. Philadelphia: WB Saunders. 1979
- Itai Y, Ohashi K, Nagai H, Murakami Y, Kokubo T, Makita K, Ohtomo K. “Ductectatic” mucinous cystadenoma and cystadenocarcinoma of the pancreas. Radiology 1986;161:697–700
- Minami M, Itai Y, Ohtomo K, Yoshida H, Yoshikawa K, Ho M. Cystic neoplasms of the pancreas: comparison of MR imaging with CT. Radiology 1989;171:53–56
- Heitzman ER. The lung: radiologic-pathologic correlations, 2nd ed. St Louis: Mosby. 1984
- Mitchell DG, Burk Jr DL, Vinitski S, Rifkin MD. The biophysical basis of tissue contrast in extracranial MR imaging. AJR 1987;149:831–837
- Mitchell DG, Mintz MC, Spritzer CE, Gussman D, Arger PH, Coleman BG, Axel L, Kressel HY. Adnexal masses: MR imaging observations at 1.5 T, with US and CT correlation. Radiology 1987;162:319–324
- Dillon WP, Som PM, Fullerton GD. Hypointense MR signal in chronically inspissated sinonasal secretions. Radiology 1990;174:73–78
- Som PM, Dillon WP, Fullerton GD, Zimmerman RA, Rajagopalan B, Marom Z. Chronically obstructed sinonasal secretions: observations on T1 and T2 shortening. Radiology 1989;172:515–520
- Itoh T, Kanaoka M, Obara A, Furuta M, Itoh H. Lymphangiosis carcinomatosa of the liver. Acta Pathol Jpn 1988;38:751–758
- Itoh T, Itoh H, Konishi J. Lymphangitic liver metastasis: radiologic-pathologic correlations. J Comput Assist Tomogr 1991;15:401–404
- Im J-G, Han MC, Yu EJ, Han JK, Park JM, Kim C-W, Seo JW, Yoon Y, Lee JD, Lee KS. Lobar bronchoalveolar carcinoma: “Angiogram Sign” on CT scans. Radiology 1990;176:749–753
- Duct ectasia due to mucus-producing cancers with intraductal extension: histopathologic correlation with radiologic imagings
Volume 20, Issue 4 , pp 341-347
- Cover Date
- Print ISSN
- Online ISSN
- Additional Links
- Mucinous cancer
- Industry Sectors
- Author Affiliations
- 1. Department of Radiology and Nuclear Medicine, Kyoto University, Faculty of Medicine, 54, Kawahara-cho, Shogoin, Sakyo-ku, 606, Kyoto, Japan
- 2. Department of Radiology, Kyoto National Hospital, 1-1, Mukaihata-cho, Fukakusa, Fushimi-ku, 612, Kyoto, Japan