Human Genetics

, Volume 86, Issue 4, pp 398–400

Localization of the human Rh blood group gene structure to chromosome region 1p34.3–1p36.1 by in situ hybridization

  • B. Chérif-Zahar
  • M. G. Mattéi
  • C. Le Van Kim
  • P. Bailly
  • J. -P. Cartron
  • Y. Colin
Original Investigations

DOI: 10.1007/BF00201843

Cite this article as:
Chérif-Zahar, B., Mattéi, M.G., Le Van Kim, C. et al. Hum Genet (1991) 86: 398. doi:10.1007/BF00201843

Summary

A cDNA clone, RhIXb (1384 bp), encoding the entire protein sequence of a human blood group Rh polypeptide has been used to map the Rh locus, by in situ hybridization, to the region p34.3–p36.1 of chromosome 1. Two other unrelated cDNA clones, pUCA2 (750bp) and pUCIII (1600 bp), isolated during the cloning procedure of the Rh cDNA were investigated simultaneously, and assigned to chromosome 3p21.1–3p22 (clone pUCA2) and to chromosome 22q12.1–22q13.1 (clone pUCIII).

Copyright information

© Springer-Verlag 1991

Authors and Affiliations

  • B. Chérif-Zahar
    • 1
  • M. G. Mattéi
    • 2
  • C. Le Van Kim
    • 1
  • P. Bailly
    • 1
  • J. -P. Cartron
    • 1
  • Y. Colin
    • 1
  1. 1.INSERM U.76, Institut National de Transfusion SanguineParisFrance
  2. 2.INSERM U.242, Centre de Génétique Médicale, Hôpital d'Enfants de la TimoneMarseille CedexFrance