Human Genetics

, Volume 85, Issue 6, pp 651–654

The human aminopeptidase N gene: isolation, chromosome localization, and DNA polymorphism analysis

Authors

  • Valerie M. Watt
    • Department of PhysiologyUniversity of Toronto
  • Huntington F. Willard
    • Department of GeneticsStanford University
Original Investigations

DOI: 10.1007/BF00193592

Cite this article as:
Watt, V.M. & Willard, H.F. Hum Genet (1990) 85: 651. doi:10.1007/BF00193592

Summary

DNA encoding the human aminopeptidase N (EC 3.4.11.2) gene (PEPN) was first isolated using rat cDNA probes and then used in Southern analysis of DNA from mouse-human somatic cell hybrids to assign this gene to the long-arm region (q11-qter) of human chromosome 15. This human genomic DNA probe detects a frequent DraIII polymorphism that is a useful marker for human chromosome 15.

Copyright information

© Springer-Verlag 1990