Journal of Molecular Evolution

, Volume 36, Issue 4, pp 396–405

A heuristic method to reconstruct the history of sequences subject to recombination

  • Jotun Hein

DOI: 10.1007/BF00182187

Cite this article as:
Hein, J. J Mol Evol (1993) 36: 396. doi:10.1007/BF00182187


Sequences subject to recombination and gene conversion defy phylogenetic analysis by traditional methods since their evolutionary history cannot be adequately summarized by a tree. This study investigates ways to describe their evolutionary history and proposes a method giving a partial reconstruction of this history. Multigene families, viruses, and alleles from within populations experience recombinations/gene conversions, so the questions studied here are relevant for a large body of data and the suggested solutions should be very practical. The method employed was implemented in a program, RecPars, written in C and was used to analyze nine retroviruses.

Key words

Phylogenetic analysis Multigene families Recombination Parsimony 

Copyright information

© Springer-Verlag 1993

Authors and Affiliations

  • Jotun Hein
    • 1
  1. 1.National Institute of GeneticsMishima, Shizuoka KenJapan
  2. 2.Institute for Genetics and EcologyAarhus University 8000 CDenmark

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