Pediatric Surgery International

, Volume 11, Issue 4, pp 269–271

Regional lymphadenitis following BCG vaccination

Authors

  • C. Merry
    • Children's Research CentreOur Lady's Hospital for Sick Children
  • R. J. Fitzgerald
    • Children's Research CentreOur Lady's Hospital for Sick Children
    • The Children's Hospital
Original Article

DOI: 10.1007/BF00178435

Cite this article as:
Merry, C. & Fitzgerald, R.J. Pediatr Surg Int (1996) 11: 269. doi:10.1007/BF00178435

Abstract

A cluster of cases of lymphadenitis occurred in Dublin following vaccination with a newly introduced Copenhagen 1331 strain of Bacille Calmette-Guerin (BCG) vaccine during 1989. All cases of BCG lymphadenitis presenting to paediatric surgical clinics over an 11-year period were reviewed to determine the optimum treatment for this problem. Seventeen patients are included, 16 of whom received vaccine in the newborn period; 1 received BCG at 8 months. Nine were treated by initial operation, 6 with antituberculous drugs, and 2 were observed without specific therapy. All but 1 of the medically treated patients and both patients who received observation only required operation for failure to resolve or progression of disease. The best results were obtained with excision and primary closure. We conclude that although sponteneous resolution occurs in a majority of all cases of BCG lymphadenitis in infants, in those patients with more severe disease who require surgical referral, a short trial of anti-microbial therapy is indicated. Patients who fail to improve or develop complications are then best treated by surgical excision of the involved nodes.

Key words

Bacille Calmette-GuerinBCG vaccineInfantLymph nodes

Copyright information

© Springer-Verlag 1996