Pediatric Surgery International

, Volume 11, Issue 4, pp 248–251

Autologous gastro-intestinal reconstruction: the composite ileo-colic loop

  • A. Bianchi
  • M. Lendon
  • I. D. Ward
Original Article

DOI: 10.1007/BF00178430

Cite this article as:
Bianchi, A., Lendon, M. & Ward, I.D. Pediatr Surg Int (1996) 11: 248. doi:10.1007/BF00178430

Abstract

A reproducible technique was developed experimentally in pigs for construction of a ‘composite bowel tube’ (CBT) made up of ileal mucosa that was grafted to a mucosally denuded colonic muscle surface vascularised by the colonic mesentery. Macroscopic and microscopic studies at terminal laparotomy revealed a viable, mucosally lined, patent peristaltic loop of bowel in six of the eight animals. Two animals died after sloughing the grafted mucosa. In vivo absorption studies, using l-alanine as an index of amino acid absorption, showed a transport pattern through the grafted mucosa of the composite ileo-colic loop appropriate to ileum when compared with controls. The CBT constitutes another autologous gastro-intestinal reconstructive technique for redistribution of available absorptive mucosa over a longer intestinal length, and may therefore be of benefit in the management of the short-bowel syndrome.

Key words

Intestinal lengtheningComposite ileo-colic loopComposite bowel tubeAutologous gastro-intestinal reconstructionShort-bowel syndrome

Copyright information

© Springer-Verlag 1996

Authors and Affiliations

  • A. Bianchi
    • 1
  • M. Lendon
    • 2
  • I. D. Ward
    • 3
  1. 1.The Royal Manchester Children's HoapitalPendleburyUK
  2. 2.The University of ManchesterUK
  3. 3.Booth Hall HospitalUK