Journal of Materials Science: Materials in Medicine

, Volume 7, Issue 6, pp 371–374

Crystallization mechanisms of calcium phosphate cement for biological uses


  • J. L. Lacout
    • Laboratoire des Matériaux-Physico-Chimie des SolidesENSCT-INP Toulouse-URA CNRS 445
  • E. Mejdoubi
    • Laboratoire de Chimie Physique GénéraleUniversité Mohammed V
  • M. Hamad
    • Laboratoire de Chimie Physique GénéraleUniversité Mohammed V

DOI: 10.1007/BF00154552

Cite this article as:
Lacout, J.L., Mejdoubi, E. & Hamad, M. J Mater Sci: Mater Med (1996) 7: 371. doi:10.1007/BF00154552


Self-setting calcium phosphate cement for dental or surgical applications can be prepared by the addition of a liquid to a mixture of acidic and basic calcium phosphate. After hardening, the final compound becomes hydroxyapatite. Using an orthogonal central composite plan, the main factors which control the setting and the final hardness of the cement were defined and models are proposed. The mechanisms of crystallization, the role of free and linked water, and the nature of the final and intermediate compounds are described.

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© Chapman & Hall 1996