, Volume 5, Issue 3, pp 363-371

Risk factors of female cancers in ragusa population (sicily) - I. Endometrium and cervix uteri cancers

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A case-control study on breast, cervix and endometrium cancer cases registered in Ragusa between January 1, 1983 and June 30, 1985 has been conducted. Information on risk factors has been obtained by means of a structured questionnaire.

Risk factors for endometrium cancer were: few children (1–2 vs > 4 OR 15.18, 95%CL 1.96–117.64), oestrogenic treatment (OR 2.20, 95%CL 1.05–4.90), obesity (Quetelet index >30 vs <22 OR 10.42, 95%CL 1.30–83.86), family history (OR 2.87, 95% CL 1.05–7.83).

Risk factors for cervix uteri cancer were: multiple abortions (>2 vs 0 OR 9.87, 95%CL 1.46–66.66), no contraception (OR 8.33, 95%CL 2.38–25.00), younger age of mother at birth (OR 6.89, 95%CL 1.71–27.70).

Age at menarche, age at menopause and years of fertile life were not found to be related to either endometrium or cervix uteri cancer.

The existence of influencing differences (ancestry, environment, lifestyle) has been postulated.

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