Photosynthesis Research

, Volume 39, Issue 3, pp 427–438

Feedback control of gene expression

  • Jen Sheen
Terrestrial photosynthesis Minireview

DOI: 10.1007/BF00014596

Cite this article as:
Sheen, J. Photosynth Res (1994) 39: 427. doi:10.1007/BF00014596


Although feedback regulation of photosynthesis by carbon metabolites has long been recognized and investigated, its underlying molecular mechanisms remain unclear. The recent discovery that glucose and acetate trigger global repression of maize photosynthetic gene transcription provides the first direct evidence that a fundamental mechanism is used for feedback regulation of photosynthesis in higher plants. The metabolic repression of photosynthetic genes has now been found in many higher plants and is likely universal. It overrides other regulation by light, tissue type and developmental stage, and serves potentially as the molecular basis of interactions between sink and source tissues. Using simplified and convenient cellular systems and transgenic plants, the study of metabolic regulation of gene expression offers an excellent opportunity for the understanding of global and coordinate gene control and metabolite-mediated signal transduction in higher plants.

Key words

acetate glucose maize metabolic repression photosynthetic genes transcription regulation 

Copyright information

© Kluwer Academic Publishers 1994

Authors and Affiliations

  • Jen Sheen
    • 1
    • 2
  1. 1.Department of GeneticsHarvard Medical SchoolBostonUSA
  2. 2.Molecular BiologyMassachusetts General HospitalBostonUSA

Personalised recommendations