Abstract
Background
Transcranial Doppler sonography (TCD) allows the continuous non-invasive assessment of intracranial blood flow velocities with high temporal resolution. It may therefore prove suitable for biofeedback of cerebral perfusion.
Purpose
The study explored whether healthy individuals can successfully be trained in self-regulation of cerebral blood flow using TCD biofeedback.
Methods
Twenty-two subjects received visual feedback of flow velocities in the middle cerebral arteries of both hemispheres. They were randomly assigned to two groups, one of which attempted to increase, the other to decrease the signal within eight training sessions. Heart rate and respiratory frequency were also monitored.
Results
Both groups achieved significant changes in flow velocities in the expected directions. Modulations in heart rate and respiratory frequency during biofeedback did not account for these effects.
Conclusions
TCD biofeedback enables efficient self-regulation of cerebral blood flow. It is promising in applications such as the treatment of migraine and post-stroke rehabilitation.
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Acknowledgements
The cooperation between the Universities of Munich and Jaén was supported by the German Academic Exchange Service and the Spanish Ministry of Education and Science. We are grateful to Stella Bollmann and Tanja Mannhart for their help with the data acquisition and analysis.
Conflicts of Interest Statement
The authors have no conflict of interest to disclose.
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Duschek, S., Schuepbach, D., Doll, A. et al. Self-regulation of Cerebral Blood Flow by Means of Transcranial Doppler Sonography Biofeedback. ann. behav. med. 41, 235–242 (2011). https://doi.org/10.1007/s12160-010-9237-x
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DOI: https://doi.org/10.1007/s12160-010-9237-x