Abstract
Background
Bone mineral density (BMD) in the proximal tibia decreases after TKA and is believed to be a factor in implant migration and loosening. Unicompartmental knee arthroplasty (UKA) is a less invasive procedure preserving knee compartments unaffected by degeneration. Finite element studies have suggested UKA may preserve BMD and that implants of differing stiffnesses might differentially affect BMD but these notions have not been clinically confirmed.
Questions/purposes
We therefore asked whether (1) proximal tibial BMD decreases after UKA, and (2) a cemented metal tibial component with a mobile polyethylene (PE) bearing would have greater BMD loss than a cemented PE tibial component.
Methods
We prospectively followed 48 patients who underwent 50 UKAs using one of two implants: one with a cemented metal tibial baseplate and a mobile PE insert (n = 26) and one with a cemented all-PE tibial component (n = 24). In followup we assessed pain and function (Oxford Knee Score, SF-12, The Knee Society Score©) and radiographs. BMD changes were assessed using quantitative CT osteodensitometry performed postoperatively and at 1 and 2 years after the index procedure.
Results
Mean cancellous BMD decreased 1.9% on the medial side and 1.1% on the lateral side. Mean cortical BMD was static, decreasing 0.4% on the medial side and increasing 0.5% on the lateral side. The greatest observed difference between implants for any region was 3.7%. There were no differences in pain or functional outcome scores.
Conclusions
BMD was preserved 2 years after UKA with no major differences seen between implant types.
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References
Abu-Rajab RB, Watson WS, Walker B, Roberts J, Gallacher SJ, Meek RM. Peri-prosthetic bone mineral density after total knee arthroplasty: cemented versus cementless fixation. J Bone Joint Surg Br. 2006;88:606–613.
Australian Orthopaedic Association National Joint Replacement Registry. Annual Report. Adelaide, Australia: Australian Orthopaedic Association; 2010.
Berger RA, Meneghini RM, Jacobs JJ, Sheinkop MB, Valle Della CJ, Rosenberg AG, Galante JO. Results of unicompartmental knee arthroplasty at a minimum of ten years of follow-up. J Bone Joint Surg Am. 2005;87:999–1006.
Borus T, Thornhill T. Unicompartmental knee arthroplasty. J Am Acad Orthop Surg. 2008;16:9–18.
Gillies RM, Hogg MC, Kohan L, Cordingley RL. Adaptive bone remodelling of all polyethylene unicompartmental tibial bearings. ANZ J Surg. 2007;77:69–72.
Gulati A, Chau R, Pandit HG, Gray H, Price AJ, Dodd CA, Murray DW. The incidence of physiological radiolucency following Oxford unicompartmental knee replacement and its relationship to outcome. J Bone Joint Surg Br. 2009;91:896–902.
Gulati A, Pandit H, Jenkins C, Chau R, Dodd CA, Murray DW. The effect of leg alignment on the outcome of unicompartmental knee replacement. J Bone Joint Surg Br. 2009;91:469–474.
Hamilton WG, Ammeen D, Engh CA Jr, Engh GA. Learning curve with minimally invasive unicompartmental knee arthroplasty. J Arthroplasty. 2010;25:735–740.
Hvid I, Bentzen SM, Jørgensen J. Remodeling of the tibial plateau after knee replacement: CT bone densitometry. Acta Orthop Scand. 1988;59:567–573.
Iesaka K, Tsumura H, Sonoda H, Sawatari T, Takasita M, Torisu T. The effects of tibial component inclination on bone stress after unicompartmental knee arthroplasty. J Biomech. 2002;35:969–974.
Klemme WR, Galvin EG, Petersen SA. Unicompartmental knee arthroplasty: sequential radiographic and scintigraphic imaging with an average five-year follow-up. Clin Orthop Relat Res. 1994;301:233–238.
Kress AM, Schmidt R, Vogel T, Nowak TE, Forst R, Mueller LA. Quantitative computed tomography-assisted osteodensitometry of the pelvis after press-fit cup fixation: a prospective ten-year follow-up. J Bone Joint Surg Am. 2011;93:1152–1157.
Levitz CL, Lotke PA, Karp JS. Long-term changes in bone mineral density following total knee replacement. Clin Orthop Relat Res. 1995;321:68–72.
Lindstrand A, Stenström A, Ryd L, Toksvig-Larsen S. The introduction period of unicompartmental knee arthroplasty is critical: a clinical, clinical multicentered, and radiostereometric study of 251 Duracon unicompartmental knee arthroplasties. J Arthroplasty. 2000;15:608–616.
Lonner JH, Klotz M, Levitz C, Lotke PA. Changes in bone density after cemented total knee arthroplasty: influence of stem design. J Arthroplasty. 2001;16:107–111.
Munro JT, Pandit S, Walker CG, Clatworthy M, Pitto RP. Loss of tibial bone density in patients with rotating- or fixed-platform TKA. Clin Orthop Relat Res. 2010;468:775–781.
New Zealand Joint Registry. Eleven Year Report. Christchurch, New Zealand: New Zealand Orthopaedic Association; 2010.
Petersen MM, Gehrchen PM, Østgaard SE, Nielsen PK, Lund B. Effect of hydroxyapatite-coated tibial components on changes in bone mineral density of the proximal tibia after uncemented total knee arthroplasty: a prospective randomized study using dual-energy x-ray absorptiometry. J Arthroplasty. 2005;20:516–520.
Price A, Waite J, Svard U. Long-term clinical results of the medial Oxford unicompartmental knee arthroplasty. Clin Orthop Relat Res. 2005;435:171-180.
Regnér LR, Carlsson LV, Kärrholm JN, Hansson TH, Herberts PG, Swanpalmer J. Bone mineral and migratory patterns in uncemented total knee arthroplasties: a randomized 5-year follow-up study of 38 knees. Acta Orthop Scand. 1999;70:603–608.
Reilly K, Munro J, Pandit S, Kress A, Walker C, Pitto RP. Inter-observer validation study of quantitative CT-osteodensitometry in total knee arthroplasty. Arch Orthop Trauma Surg. 2007;127:729–731.
Sadoghi P, Leithner A, Weber P, Friesenbichler J, Gruber G, Kastner N, Pohlmann K, Jansson V, Wegener B. Radiolucent lines in low-contact-stress mobile-bearing total knee arthroplasty: a blinded and matched case control study. BMC Musculoskelet Disord. 2011;12:142.
Sarmah SS, Patel S, Hossain FS, Haddad FS. The radiological assessment of total and unicompartmental knee replacements. J Bone Joint Surg Br. 2012;94:1321–1329.
Sawatari T, Tsumura H, Iesaka K, Furushiro Y, Torisu T. Three-dimensional finite element analysis of unicompartmental knee arthroplasty: the influence of tibial component inclination. J Orthop Res. 2005;23:549–554.
Schmidt R, Pitto RP, Kress A, Ehremann C, Nowak TE, Reulbach U, Forst R, Müller L. Inter- and intraobserver assessment of periacetabular osteodensitometry after cemented and uncemented total hip arthroplasty using computed tomography. Arch Orthop Trauma Surg. 2005;125:291–297.
Schreiber JJ, Anderson PA, Rosas HG, Buchholz AL, Au AG. Hounsfield units for assessing bone mineral density and strength: a tool for osteoporosis management. J Bone Joint Surg Am. 2011;93:1057–1063.
Shetty NR, Hamer AJ, Kerry RM, Stockley I, Eastell R, Wilkinson JM. Bone remodelling around a cemented polyethylene cup: a longitudinal densitometry study. J Bone Joint Surg Br. 2006;88:455–459.
Soininvaara TA, Miettinen HJ, Jurvelin JS, Suomalainen OT, Alhava EM, Kröger HP. Periprosthetic tibial bone mineral density changes after total knee arthroplasty: one-year follow-up study of 69 patients. Acta Orthop Scand. 2004;75:600–605.
Squire MW, Callaghan JJ, Goetz DD, Sullivan PM, Johnston RC. Unicompartmental knee replacement: a minimum 15 year followup study. Clin Orthop Relat Res. 1999;367:61–72.
Stewart HD, Newton G. Long-term results of the Manchester knee: surface arthroplasty of the tibiofemoral joint. Clin Orthop Relat Res. 1992;278:138–146.
Therbo M, Petersen MM, Varmarken JE, Olsen CA, Lund B. Influence of pre-operative bone mineral content of the proximal tibia on revision rate after uncemented knee arthroplasty. J Bone Joint Surg Br. 2003;85:975–979.
Warming L, Hassager C, Christiansen C. Changes in bone mineral density with age in men and women: a longitudinal study. Osteoporos Int. 2002;13:105–112.
Weale AE, Murray DW, Baines J, Newman JH. Radiological changes five years after unicompartmental knee replacement. J Bone Joint Surg Br. 2000;82:996–1000.
Zannoni C, Viceconti M, Pierotti L, Cappello A. Analysis of titanium induced CT artifacts in the development of biomechanical finite element models. Med Eng Phys. 1998;20:653-659.
Acknowledgments
We thank Rocco P. Pitto MD, PhD, FRACS at the University of Auckland for assistance with the quantitative CT osteodensitometry analysis and Richard Feltham MBChB, FRANZCR, at Taranaki Base Hospital for assistance with CT scanning protocols and reports for the National Radiation Laboratory.
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The institution of one or more of the authors (SVH, TGL) has received, during the study period, funding from the Taranaki Medical Foundation.
All ICMJE Conflict of Interest Forms for authors and Clinical Orthopaedics and Related Research editors and board members are on file with the publication and can be viewed on request.
This work was performed at the Taranaki Base Hospital, New Plymouth, New Zealand.
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Richmond, B.I., Hadlow, S.V., Lynskey, T.G. et al. Proximal Tibial Bone Density Is Preserved After Unicompartmental Knee Arthroplasty. Clin Orthop Relat Res 471, 1661–1669 (2013). https://doi.org/10.1007/s11999-013-2784-2
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DOI: https://doi.org/10.1007/s11999-013-2784-2