Skip to main content
Log in

Heparin and Aspirin Versus Aspirin Alone for Prevention of Recurrent Pregnancy Loss

  • Clinical Trial Report
  • Published:
Current Rheumatology Reports Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Rai R, Cohen H, Dave M, Regan L: Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies. BMJ 1997, 314:253–257.

    CAS  PubMed  Google Scholar 

  2. Kutteh WH: Antiphospholipid antibody-associated recurrent pregnancy loss: treatment with heparin and low-dose aspirin is superior to low-dose aspirin alone. Am J Obstet Gynecol 1996, 174:1584–1589.

    Article  CAS  PubMed  Google Scholar 

  3. Farquharson RG, Quenby S, Greaves M: Antiphospholipid syndrome in pregnancy: a randomized, controlled trial of treatment. Obstet Gynecol 2002, 100:408–413.

    Article  CAS  PubMed  Google Scholar 

  4. Laskin CA, Spitzer KA, Clark CA, et al.: Low molecular weight heparin and aspirin for recurrent pregnancy loss: results from the randomized, controlled HepASA Trial. J Rheumatol 2009, 36:279–287.

    Article  CAS  PubMed  Google Scholar 

  5. Cowchock FS, Reece EA, Balaban D, et al.: Repeated fetal losses associated with antiphospholipid antibodies: a collaborative randomized trial comparing prednisone to low-dose heparin treatment. Am J Obstet Gynecol 1992, 166:1318–1323.

    CAS  PubMed  Google Scholar 

  6. Franklin RD, Kutteh WH: Antiphospholipid antibodies (APA) and recurrent pregnancy loss: treating a unique APA positive population. Hum Reprod 2002, 17:2981–2985.

    Article  CAS  PubMed  Google Scholar 

  7. Noble LS, Kutteh WH, Lashey N, et al.: Antiphospholipid antibodies associated with recurrent pregnancy loss: prospective, multicenter, controlled pilot study comparing treatment with low-molecular-weight heparin versus unfractionated heparin. Fertil Steril 2005, 83:684–690.

    Article  CAS  PubMed  Google Scholar 

  8. Pattison NS, Chamley LW, Birdsall M, et al.: Does aspirin have a role in improving pregnancy outcome for women with the antiphospholipid syndrome? A randomized controlled trial. Am J Obstet Gynecol 2000, 183:1008–1012.

    Article  CAS  PubMed  Google Scholar 

Download references

Disclosure

Dr. Roubey is a consultant for Quest Diagnostics.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Robert A. S. Roubey.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Roubey, R.A.S. Heparin and Aspirin Versus Aspirin Alone for Prevention of Recurrent Pregnancy Loss. Curr Rheumatol Rep 12, 1–3 (2010). https://doi.org/10.1007/s11926-009-0076-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11926-009-0076-3

Keywords

Navigation