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Modulation of left ventricular dilation remodeling with epicardial restraint devices in postmyocardial infarction heart failure

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Abstract

Myocardial infarction initiates progressive changes in the biology of the myocyte and nonmyocyte components of the myocardium, as well as the geometry of the left ventricle. Despite the use of evidence-based strategies to postmyocardial infarction, heart failure supervenes and is attended by an unacceptably high mortality rate. Given that left ventricular (LV) remodeling may contribute independently to disease progression, several innovative approaches have been designed to attenuate and reverse LV remodeling. This review discusses the emerging role of epicardial restraint devices in the treatment of postmyocardial cardiac remodeling.

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Authors and Affiliations

  1. Cardiovascular Division, Washington University School of Medicine, 660 South Euclid Avenue, Campus PO Box 8066, Saint Louis, MO, 63110, USA

    Douglas L. Mann

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  1. Veli K. Topkara
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  2. Srikanth Kondareddy
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  3. Douglas L. Mann
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Correspondence to Douglas L. Mann.

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Topkara, V.K., Kondareddy, S. & Mann, D.L. Modulation of left ventricular dilation remodeling with epicardial restraint devices in postmyocardial infarction heart failure. Curr Heart Fail Rep 6, 229–235 (2009). https://doi.org/10.1007/s11897-009-0032-6

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