Skip to main content

Advertisement

SpringerLink
Log in

Defects in Interleukin-17 Immunity in the Pathogenesis of Chronic Mucocutaneous Candidiasis

  • Clinical Trial Report
  • Published:
Current Allergy and Asthma Reports Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Holland SM, Vinh DC. Yeast infections—human genetics on the rise. New Engl J Med. 2009;361:1798–801.

    Article  PubMed  CAS  Google Scholar 

  2. Puel A, Doffinger R, Natividad A, et al. Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I. J Exp Med. 2010;207:291–7.

    Article  PubMed  CAS  Google Scholar 

  3. Kisand K, Boe Wolff AS, Podkrajsek KT, et al. Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines. J Exp Med. 2010;207:299–308.

    Article  PubMed  CAS  Google Scholar 

  4. Minegishi Y, Saito M, Nagasawa M, et al. Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome. J Exp Med. 2009;206:1291–301.

    Article  PubMed  CAS  Google Scholar 

  5. Ferwerda B, Ferwerda G, Plantinga TS, et al. Human dectin-1 deficiency and mucocutaneous fungal infections. New Engl J Med. 2009;361:1760–7.

    Article  PubMed  CAS  Google Scholar 

  6. Glocker E-O, Hennigs A, Nabavi M, et al. A homozygous CARD9 mutation in a family with susceptibility to fungal infections. New Engl J Med. 2009;361:1727–35.

    Article  PubMed  CAS  Google Scholar 

  7. de Beaucoudrey L, Puel A, Filipe-Santos O, et al. Mutations in STAT3 and IL12RB1 impair the development of human IL-17-producing T cells. J Exp Med. 2008;205(7):1543–50.

    Article  PubMed  Google Scholar 

  8. Wells RS, Higgs JM, Macdonald A, et al. Familial chronic muco-cutaneous candidiasis. J Med Genet. 1972;9(3):302–10.

    Article  PubMed  CAS  Google Scholar 

  9. Canales L, Middlemas 3rd RO, Louro JM, et al. Immunological observations in chronic mucocutaneous candidiasis. Lancet. 1969;294:567–71.

    Article  Google Scholar 

  10. Korn T, Bettelli E, Oukka M, et al. IL-17 and Th17 cells. Annu Rev Immunol. 2009;27:485–517.

    Article  PubMed  CAS  Google Scholar 

  11. Aujla SJ, Dubin PJ, Kolls JK. Th17 cells and mucosal host defense. Semin Immunol. 2007;19:377–82.

    Article  PubMed  CAS  Google Scholar 

  12. Hueber W, Patel DD, Dryja T, et al. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci Transl Med. 2010;2:52ra72.

    Article  PubMed  Google Scholar 

  13. Wang YH, Voo KS, Liu B, et al. A novel subset of CD4+ TH2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma. J Exp Med. 2010;207:2479–91.

    Article  PubMed  CAS  Google Scholar 

  14. Martinez-Moczygemba M, Doan ML, Elidemir O, et al. Pulmonary alveolar proteinosis caused by deletion of the GM-CSFRalpha gene in the X chromosome pseudoautosomal region 1. J Exp Med. 2008;205:2711–6.

    Article  PubMed  CAS  Google Scholar 

  15. Takuji S, Sakagami T, Rubin BK, et al. Familial pulmonary proteinosis caused by mutations in CSF2RA. J Exp Med. 2008;205:2703–10.

    Article  Google Scholar 

  16. Kitamura T, Tanaka N, Watanabe K, et al. Idiopathic pulmonary proteinosis as an autoimmune disease with neutralizing antibody against granulocyte/macrophage colony stimulating factor. J Exp Med. 1999;190:875–80.

    Article  PubMed  CAS  Google Scholar 

  17. Martinez-Moczygemba M, Huston DP. Immune dysregulation in the pathogenesis of pulmonary alveolar proteinosis. Curr Allergy Asthma Rep. 2010;10:320–5.

    Article  PubMed  CAS  Google Scholar 

  18. van de Veerdonk FL, Plantinga TS, Hoischen A, et al. STAT1 mutations in autosomal dominant chronic mucocutaneous candidiasis. N Engl J Med. 2011;365:54-61.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Departments of Microbial and Molecular Pathogenesis and Medicine, College of Medicine and Clinical Science and Translational Research Institute, Texas A&M Health Science Center, 2121 West Holcombe Boulevard, Suite 803, Houston, TX, 77030, USA

    David P. Huston

Authors
  1. David P. Huston
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to David P. Huston.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Huston, D.P. Defects in Interleukin-17 Immunity in the Pathogenesis of Chronic Mucocutaneous Candidiasis. Curr Allergy Asthma Rep 11, 342–344 (2011). https://doi.org/10.1007/s11882-011-0209-4

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11882-011-0209-4

Keywords

Search

Navigation