Skip to main content

Advertisement

Log in

Anti-glycolipid GM2-positive Guillain–Barre syndrome due to hepatitis E infection

  • Brief Report
  • Published:
Irish Journal of Medical Science Aims and scope Submit manuscript

Abstract

Background

Hepatitis E infection is most prevalent in developing countries with poor sanitation, but can also occur apparently sporadically in more developed areas.

Case

We here report a second European case of Guillain–Barre syndrome due to hepatitis E infection in association with anti-glycolipid GM2 antibody.

Interpretation

This is likely to be a specific association involving molecular mimicry, and further European cases can therefore be expected.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

References

  1. Aggarwal R, Naik S (2009) Epidemiology of hepatitis E: current status. J Gastroenterol Hepatol 24:1484–1493

    Article  PubMed  Google Scholar 

  2. Loly JP, Rikir E, Seivert M et al (2009) Guillain–Barre syndrome following hepatitis E. World J Gastroenterol 15:1645–1647

    Article  PubMed  Google Scholar 

  3. Sood A, Midha V, Sood N (2000) Guillain–Barre syndrome with acute hepatitis E. Am J Gastroenterol 95:3667–3668

    CAS  PubMed  Google Scholar 

  4. Kamani P, Baijal R, Amarapurkar D et al (2005) Guillain–Barre syndrome associated with acute hepatitis E. Indian J Gastroenterol 24:216

    PubMed  Google Scholar 

  5. Kumar R, Bhoi S, Kumar M et al (2002) Guillain–Barre syndrome and acute hepatitis E: a rare association. J Indian Acad Clin Med 3:389–391

    Google Scholar 

  6. Ono S, Chida K, Takasu T (1994) Guillain–Barre syndrome following fulminant viral hepatitis A. Intern Med 33:799–801

    Article  CAS  PubMed  Google Scholar 

  7. Tsukada N, Koh C, Inoue A et al (1987) Demyelinating neuropathy associated with hepatitis B virus infection. J Neurol Sci 77:203–216

    Article  CAS  PubMed  Google Scholar 

  8. Klippel N, Hautekeete M, Keyser J et al (1993) Guillain–Barre syndrome as the presenting manifestation of hepatitis C infection. Neurology 43:2143

    PubMed  Google Scholar 

  9. Lin S, Ryu S, Liaw Y (1989) Guillain–Barre syndrome associated with acute delta hepatitis virus superinfection. J Med Virol 28:144–145

    Article  CAS  PubMed  Google Scholar 

  10. Yadav K, Rohatgi A, Sharma S et al (2002) Oculomotor palsy associated with hepatitis E infection. J Assoc Physicians India 50:731

    Google Scholar 

  11. Kejariwal D, Roy S, Sarkar N (2001) Seizure associated with acute hepatitis E. Neurology 57:1935

    CAS  PubMed  Google Scholar 

  12. Mandal K, Chopra N (2006) Acute transverse myelitis following hepatitis E virus infection. Indian Pediatr 43:365–366

    PubMed  Google Scholar 

  13. Fong F, Illahi M (2009) Neuralgia amyotrophy associated with hepatitis E virus. Clin Neurol Neurosurg 111:193–195

    Article  PubMed  Google Scholar 

  14. Kamar N, Izopet J, Cintas P et al (2010) Hepatitis E virus-induced neurological symptoms in a kidney-transplant patient with chronic hepatitis. Am J Transplant 10:1321–1324

    Article  CAS  PubMed  Google Scholar 

  15. Dalton H, Bendall R, Ijaz S et al (2008) Hepatitis E: an emerging infection in developed countries. Lancet Infect Dis 8:698–709

    Article  PubMed  Google Scholar 

  16. Hughes R, Cornblath D (2005) Guillain–Barre syndrome. Lancet 366:1653–1656

    Article  CAS  PubMed  Google Scholar 

  17. Carpo M, Pedotti R, Allaria S et al (1999) Clinical presentation and outcome of Guillain–Barre and related syndromes in relation to anti-ganglioside antibodies. J Neurol Sci 168:178–184

    Article  Google Scholar 

  18. Hartnung HP, Kieseier R (1999) Antibody responses in the Guillain–Barre syndrome. J Neurol Sci 168:75–77

    Article  Google Scholar 

  19. Sheikh K, Ho T, Nachamkin I et al (1998) Molecular mimicry in Guillain–Barre syndrome. Ann N Y Acad Sci 845:307–321

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to K. O’Rourke.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cronin, S., McNicholas, R., Kavanagh, E. et al. Anti-glycolipid GM2-positive Guillain–Barre syndrome due to hepatitis E infection. Ir J Med Sci 180, 255–257 (2011). https://doi.org/10.1007/s11845-010-0635-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11845-010-0635-7

Keywords

Navigation