Skip to main content
Log in

Surgical left ventricular reconstruction

  • Current Topics Review Article
  • Published:
General Thoracic and Cardiovascular Surgery Aims and scope Submit manuscript

Abstract

Because of the shortage of donors for heart transplantation, surgical ventricular reconstruction (SVR) has been under development to treat end-stage heart failure due to a dilated left ventricle. The operative procedures have been developed and modified based on the clinical results and preoperative findings of several examinations. SVR is performed to reduce the size and volume of the ventricle as well as to reshape it. The procedures, which differ based on the particular left ventricular lesion, are endoventricular patch plasty or septal anterior ventricular restoration for anteroseptal exclusion and partial left ventriculectomy or a posterior restoration procedure for posterolateral exclusion. In the indicated patients, SVR has been emerging as an alternative to heart transplantation. The accumulating surgical knowledge may provide new opportunities for the treatment of ischemic dilated cardiomyopathy. The Surgical Treatment for Ischemic Heart Failure (STICH) trial seems to have arrived at a misguided conclusion. Surgeons have to know not only the operative procedures for SVR; they must also be aware of the systolic and diastolic functioning and the volume and size of the left ventricle before and after SVR. Hence, SVR is reviewed and discussed here.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Cooley DA. Ventricular endoaneurysmorrhaphy: a simplified repair for extensive postinfarction aneurysm. J Card Surg 1989;4:200–205.

    Article  PubMed  CAS  Google Scholar 

  2. Dor V, Kreitmann P, Jourdan J, Acar C, Saab M, Coste P. Interest of physiological closure (circumferential plasty on contractive areas) of left ventricle after resection and endocardectomy for aneurysm or akinetic zone comparison with classical technique about a series of 209 left ventricular resections. J Cardiovasc Surg 1985;26:73 (abstract).

    Google Scholar 

  3. Dor V, Sabatier M, Di Donato M, Montiglio F, Toso A, Maioli M. Efficacy of endoventricular patch plasty in large postinfarction akinetic scar and severe left ventricular dysfunction: comparison with a series of large dyskinetic scars. J Thorac Cardiovasc Surg 1998;116:50–59.

    Article  PubMed  CAS  Google Scholar 

  4. Batista RJ, Verde J, Nery P, Bocchino L, Takeshita N, Bhayana JN, et al. Partial left ventriculectomy to treat endstage heart disease. Ann Thorac Surg 1997;64:634–638.

    Article  PubMed  CAS  Google Scholar 

  5. Dor V. Left ventricular reconstruction: the aim and the reality after twenty years. J Thorac Cardiovasc Surg 2004;128:17–20.

    Article  PubMed  Google Scholar 

  6. Dor V. Left ventricular aneurysms: the endoventricular circular patch plasty. Semin Thorac Cardiovasc Surg 1997;9:123–130.

    PubMed  CAS  Google Scholar 

  7. Dor V, Saab M, Montiglio F. Left ventricular aneurysm: a new surgical approach. Thorac Cardiovasc Surg 1989;37:11–19.

    Article  PubMed  CAS  Google Scholar 

  8. Bogaert J, Rademakers FE. Regional nonuniformity of normal adult human left ventricle. Am J Physiol Heart Circ Physiol 2001;280:H610–H620.

    PubMed  CAS  Google Scholar 

  9. Athanasuleas CL, Stanley AWH Jr, Buckberg GD, Dor V, DiDonato M, Blackstone EH, et al. Surgical anterior ventricular endocardial restoration (SAVER) in the dilated remodelled ventricle after anterior myocardial infarction: RESTORE group-reconstructive endoventricular surgery, returning torsion original radius elliptical shape to the LV. J Am Coll Cardiol 2001;37:1199–1209.

    Article  PubMed  CAS  Google Scholar 

  10. Batista R. Partial left ventriculectomy: the Batista procedure. Eur J Cardiothorac Surg 1999;15:12–19.

    Article  Google Scholar 

  11. Ascione R, Lim KH, Chamberlain M, Al Ruzzeh S, Angelini GD. Early and late results of partial left ventriculectomy: single center experience and review of literature. J Card Surg 2003;18:190–196.

    Article  PubMed  Google Scholar 

  12. Isomura T, Notomi Y, Hoshino J, Fukada Y, Katahira S, Kitamura A, et al. Indication of posterior restoration and surgical results in patients with dilated cardiomyopathy. Eur J Cardiothorac Surg 2010;38:171–175.

    Article  PubMed  Google Scholar 

  13. Dor V, Civaia F, Alexandrescu C, Montiglio F. The postmyocardial infarction scarred ventricle and congestive heart failure: the preeminence of magnetic resonance imaging for preoperative, intraoperative, and postoperative assessment. J Thorac Cardiovasc Surg 2008;136:1405–1412.

    Article  PubMed  Google Scholar 

  14. Pennell DJ, Sechtem UP, Higgins CB, Manning WJ, Pohost GM, Rademakers FE, et al. Clinical indications for cardiovascular magnetic resonance (CMR): Consensus Panel report. Eur Heart J 2004;25:1940–1965.

    Article  PubMed  Google Scholar 

  15. Mahrholdt H, Wagner A, Judd RM, Sechtem U. Assessment of myocardial viability by cardiovascular magnetic resonance imaging. Eur Heart J 2002;23:612–619.

    Article  Google Scholar 

  16. Bellenger NG, Burgess MI, Ray SG, Lahiri A, Coats AJ, Cleland JG, et al. Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide, ventriculography and cardiovascular magnetic resonance: are they interchangeable? Eur Heart J 2000;21:1295–1297.

    Article  Google Scholar 

  17. Isomura T, Suma H, Horii T, Sato T, Kikuchi N. Partial left ventriculectomy, ventriculoplasty or valvular surgery for idiopathic dilated cardiomyopathy: the role of intra-operative echocardiography. Eur J Cardiothorac Surg 2000;17:239–245.

    Article  PubMed  CAS  Google Scholar 

  18. Becker M, Hoffmann R, Kuhl M. Analysis of myocardial deformation based on ultrasonic pixel tracking to determine transmurality in chronic myocardial infarction. Eur Heart J 2006;27:2560–2566.

    Article  PubMed  Google Scholar 

  19. Popovic Z, Benejam B, Bian C. Speckle-tracking echocardiography correctly identifies segmental left ventricular dysfunction induced by scarring in a rat model of myocardial infarction. Am J Physiol Heart Circ Physiol 2007;292:2809–2816.

    Article  Google Scholar 

  20. McKay RG, Pfeffer MA, Pasternak RC, Markis JE, Come PC, Nakao S, et al. Left ventricular remodeling after myocardial infarction: a corollary to infarct expansion. Circulation 1986;74:693–702.

    PubMed  CAS  Google Scholar 

  21. Yamaguchi A, Ino T, Adachi H, Mizuhara A, Murata S, Kamio H. Left ventricular end-systolic volume index in patients with ischemic cardiomyopathy predicts postoperative ventricular function. Ann Thorac Surg 1995;60:1059–1062.

    Article  PubMed  CAS  Google Scholar 

  22. Di Donato M, Toso A, Maioli M. Intermediate survival and predictors of death after surgical ventricular restoration. Semin Thorac Cardiovasc Surg 2001;13:468–475.

    PubMed  Google Scholar 

  23. Maxey TS, Reece TB, Ellman PI, Butler, Kern JA, Kron IL, et al. Coronary artery bypass with ventricular restoration is superior to coronary artery bypass alone in patients with ischemic cardiomyopathy. J Thorac Cardiovasc Surg 2004;127:428–434.

    Article  PubMed  Google Scholar 

  24. Dor V, Sabatier M, Montiglio F, Civaia F, DiDonato M. Endoventricular patch reconstruction of ischemic failing ventricle: a single center with 20 years experience-advantages of magnetic resonance imaging assessment. Heart Fail Rev 2004;9:269–286.

    Article  PubMed  CAS  Google Scholar 

  25. Klein P, Bax JJ, Shaw LJ, Feringa HH, Versteegh MII, Dion RAD, et al. Early and late outcome of left ventricular reconstruction surgery in ischemic heart disease. Eur J Cardiothorac Surg 2008;34:1149–1157.

    Article  PubMed  Google Scholar 

  26. Sartipy U, Albåge A, Mattsson E, Lindblom DR. Edge-toedge mitral repair without annuloplasty in combination with surgical ventricular restoration. Ann Thorac Surg 2007;83:1303–1309.

    Article  PubMed  Google Scholar 

  27. Tavakoli R, Bettex D, Weber A, Brunner H, Genono M, Pretre R, et al. Repair of postinfarction dyskinetic LV aneurysm with either linear or patch technique. Eur J Cardiothorac Surg 2002;22:129–134.

    Article  PubMed  Google Scholar 

  28. Ural E, Yuksel H, Pehlivanoglu S, Bakay C, Olga R. Short and long term survival of surgical treatment of left ventricular aneurysms: ten years experience. Jpn Heart J 2002;43:379–387.

    Article  PubMed  Google Scholar 

  29. Vicol C, Rupp G, Fischer S, Summer C, Dietrich Bolte H. Linear repair versus ventricular reconstruction for the treatment of left ventricular aneurysm: a 10-year experience. J Cardiovasc Surg 1998;39:461–468.

    CAS  Google Scholar 

  30. White HD, Norris RM, Brown MA, Brandt PW, Whitlock RM, Wild CJ. Left ventricular end-systolic volume as the major determinant of survival after recovery from myocardial infarction. Circulation 1987;76:44–51.

    PubMed  CAS  Google Scholar 

  31. Otsuji Y, Handschumacher MD, Levine RA. Insights from three-dimensional echocardiography into the mechanism of functional mitral regurgitation: direct in vivo demonstration of altered leaflet tethering geometry. Circulation 1997;96:1999–2008.

    PubMed  CAS  Google Scholar 

  32. Buckberg GD. Questions and answers about the STICH trial: a different perspective. J Thorac Cardiovasc Surg 2005;130:245–249.

    Article  PubMed  Google Scholar 

  33. Hvass U, Tapia M, Baron F, Pouzet B, Shafy A. Papillary muscle sling: a new functional approach to mitral repair in patients with ischemic left ventricular dysfunction and functional mitral regurgitation. Ann Thorac Surg 2003;75:809–811.

    Article  PubMed  Google Scholar 

  34. Takeda K, Matsumiya G, Matsue H, Sakaki M, Sakaguchi T, Sawa Y. Left Ventricular Reconstructive Surgery in Ischemic Dilated Cardiomyopathy Complicated With Cardiogenic Shock. Ann Thorac Surg 2008;85:1339–1343.

    Article  PubMed  Google Scholar 

  35. Patel ND, Williams JA, Nwakanma LU, Waldron MM, Bluemke DA, Conte JV. Surgical Ventricular Restoration for Advanced Congestive Heart Failure: Should Pulmonary Hypertension Be a Contraindication? Ann Thorac Surg 2006;82:873–878.

    Article  Google Scholar 

  36. Tulner SAF, Bleeker GB Steendijk P, Klautz RJM, Bax JJ, Schalij MJ, et al. Surgical ventricular restoration in patients with ischemic dilated cardiomyopathy: evaluation of systolic and diastolic ventricular function, wall stress, dyssynchrony, and mechanical efficiency by pressure-volume loops. J Thorac Cardiovasc Surg 2006;132:459–463.

    Article  Google Scholar 

  37. Tulner SAF, Bax JJ, Bleeker GB, Steendijk P, Klautz RJM, Holman ER, et al. Beneficial hemodynamic and clinical effects of surgical ventricular restoration in patients with ischemic dilated cardiomyopathy. Ann Thorac Surg 2006;82:1721–1727.

    Article  PubMed  Google Scholar 

  38. Adams JD, Fedoruk LM, Tache-Leon CA, Peeler BB, Kern JA, Tribble CG, et al. Does preoperative ejection fraction predict operative mortality with left ventricular restoration? Ann Thorac Surg 2006;82:1715–1719; discussion 1719–20.

    Article  PubMed  Google Scholar 

  39. Di Donato M, Toso A, Maioli M, Sabatier M, Stanley AW Jr, Dor V, et al. Intermediate survival and predictors of death after surgical ventricular restoration. Semin Thorac Cardiovasc Surg 2002;13:468–475.

    Google Scholar 

  40. Menicanti L, Castelvecchio S, Ranucci M, Frigiola A, Santambrogio C, de Vincentiis C, et al. Surgical therapy for ischemic heart failure: single centre experience with surgical anterior ventricular resoration. J Thorac Cardiovasc Surg 2007;134:433–441.

    Article  PubMed  Google Scholar 

  41. Menicanti M, Di Donato M. The Dor procedure: what has changed after fifteen years of clinical practice? J Thorac Cardiovasc Surg 2002;124:886–890.

    Article  PubMed  Google Scholar 

  42. Di Donato M, Sabatier M, Dor V, Gensini GF, Toso A. Effects of the Dor procedure on left ventricular dimension and shape and geometric correlates of mitral regurgitation one year after surgery. Thorac Cardiovasc Surg 2001;121:91–96.

    Article  Google Scholar 

  43. Otuji Y, Kumanohosa T, Yoshifuku S, Matsukida K, Koriyama C, Kisanuki A, et al. Isolated annular dilation does not usually cause important functional mitral regurgitation: comparison between patients with lone atrial fibrillation and those with idiopathic or ischemic cardiomyopathy. J Am Coll Cardiol 2002;39:1651–1656.

    Article  Google Scholar 

  44. Maisano F, Torracca L, Oppizzi M, Stefano PL, D’Addario G, La Canna G, et al. The edge-to-edge technique: a simplified method to correct mitral insufficiency. Eur J Cardiothorac Surg 1998;13:240–245.

    Article  PubMed  CAS  Google Scholar 

  45. Dor V, Di Donato M, Sabatier M, Montiglio F, Civaia F, RESTORE Group. Left ventricular reconstruction by endoventricular circular patch plasty repair: a 17-year experience. Semin Thorac Cardiovasc Surg 2001;13:435–447.

    PubMed  CAS  Google Scholar 

  46. Isomura T, Horii T, Suma H, Buckberg GD, RESTORE Group. Septal anterior ventricular exclusion operation (pacopexy) for ischemic dilated cardiomyopathy: treat form not disease. Eur J Cardiothorac Surg 2006;29:245–250.

    Article  Google Scholar 

  47. Ueno T, Sakata R, Iguro Y, Yamamoto H, Ueno M, Ueno T, et al. Mid-term changes of left ventricular geometry and function after Dor, SAVE, and overlapping procedures. Eur J Cardiothorac Surg 2007;32:52–57.

    Article  PubMed  Google Scholar 

  48. Subramanian H, Kunadian B, Dunning JA. Is it worth performing surgical ventricular restoration in patients with ischemic cardiomyopathy and akinetic but non-aneurysmal segments in the left ventricle? Interact Cardiovasc Thorac Surg 2008;7:702–707.

    Article  PubMed  Google Scholar 

  49. Athanasuleas CL, Buckberg GD, Dor V, RESTORE group. Surgical ventricular restoration in the treatment of congestive heart failure due to post-infarction ventricular dilation. J Am Coll Cardiol 2004;44:1439–1445.

    Article  PubMed  Google Scholar 

  50. Maxey TS, Reece TB, Ellman PI, Butler PD, Kern JA, Tribble CG, et al. Coronary artery bypass with ventricular restoration is superior to coronary artery bypass alone in patients with ischemic cardiomyopathy. J Thorac Cardiovasc Surg 2004;127:428–434.

    Article  PubMed  Google Scholar 

  51. Aguiar Ribeiro GC, Antoniali F, Lopes MM. Left ventricular reconstruction brings benefit for patients with ischemic cardiomyopathy. J Card Fail 2006;12:189–194.

    Article  PubMed  Google Scholar 

  52. Isomura T, Suma H, Yamaguchi A, Kobashi T, Yuda A. Left ventricular restoration for ischemic cardiomyopathycomparison of presence and absence of mitral procedure. Eur J Cardiothorac Surg 2003;23:614–619.

    Article  PubMed  Google Scholar 

  53. Mickleborough LL, Merchant N, Ivanov J, Rao V, Carson S. Left ventricular reconstruction: early and late results. J Thorac Cardiovasc Surg 2004;128:27–37.

    Article  PubMed  Google Scholar 

  54. Ribeiro GA, da Costa CE, Lopes MM, Albuquerque AN, Antoniali F, Reinert GAA, et al. Left ventricular reconstruction benefits patients with ischemic cardiomyopathy and nonviable myocardium. Eur J Cardiothorac Surg 2006;29:196–201.

    Article  PubMed  Google Scholar 

  55. Couper GS, Bunton RW, Birjiniuk V. Relative risks of left ventricular aneurysmectomy in patients with akinetic scars versus true dyskinetic aneurysms. Circulation 1990;82:IV248–IV256.

    PubMed  CAS  Google Scholar 

  56. Yiannikas J, MacIntyre WJ, Underwood DA. Prediction of improvement in left ventricular function after ventricular aneurysmectomy using Fourier phase and amplitude analysis of radionuclide cardiac blood pool scans. Am J Cardiol 1985;55:1308–1312.

    Article  PubMed  CAS  Google Scholar 

  57. Mitchell GF, Lamas GA, Vaughan DE, Pfeffer MA. Left ventricular remodeling in the year after first anterior myocardial infarction: a quantitative analysis of contractile segment lengths and ventricular shape. J Am Coll Cardiol 1992;19:1136–1144.

    Article  PubMed  CAS  Google Scholar 

  58. Micklebrough LL, Carson S, Ivanov J. Repair of dyskinetic or akinetic left ventricular aneurysm: results obtained with a modified linear closure. J Thorac Cardiovasc Surg 2001;121:675–682.

    Article  Google Scholar 

  59. Jones RH, Velazquez EJ, Michler RE, Sopko G, Oh JK, O’Connor CM, et al. Coronary bypass surgery with or without surgical ventricular reconstruction. N Engl J Med 2009;360:1705–1717.

    Article  PubMed  CAS  Google Scholar 

  60. Buckberg GD, Athanasuleas CL. The STICH trial: misguided conclusions. J Thorac Cardiovasc Surg 2009;138:1060–1064.

    Article  PubMed  Google Scholar 

  61. Bolling SF, Pagani FD, Deeb GM, Bach BS. Intermediateterm outcome of mitral reconstruction in cardiomyopathy. J Thorac Cardiovasc Surg 1998;115:381–388.

    Article  PubMed  CAS  Google Scholar 

  62. Wu AH, Aaronson KD, Bolling SF, Pagani FD, Welch K, Koelling TM. Impact of mitral valve annuloplasty on mortality risk in patients with mitral regurgitation and left ventricular systolic dysfunction. Am Coll Cardiol 2005;45:381–387.

    Article  Google Scholar 

  63. Ascione R, Lim KH, Chamberlain M, Al Ruzzeh S, Angelini GD. Early and late results of partial left ventriculectomy: single center experience and review of the literature. J Card Surg 2003;18:190–196.

    Article  PubMed  Google Scholar 

  64. Suma H. Left ventriculoplasty for nonischemic dilated cardiomyopathy. Semin Thorac Cardiovasc Surg 2001;13:514–521.

    PubMed  CAS  Google Scholar 

  65. Buckberg GD, Coghlan HC, Torrent-Guasp F. The structure and function of the helical heart and its buttress wrapping. VI. Geometric concepts of heart failure and use for structural correction. Semin Thorac Cardiovasc Surg 2001;13:386–401.

    PubMed  CAS  Google Scholar 

  66. Suma H, Isomura T, Horii T, Buckberg G, Restore Group. Role of site selection for left ventriculoplasty to treat idiopathic dilated cardiomyopathy. Heart Fail Rev 2005;9:329–333.

    Article  Google Scholar 

  67. Franco-Cereceda A, McCarthy PM, Blackstone EH, Hoercher KJ, White JA, Young JB, et al. Partial left ventriculectomy for dilated cardiomyopathy: is this an alternative to transplantation? J Thorac Cardiovasc Surg 2001;121:879–893.

    Article  PubMed  CAS  Google Scholar 

  68. Emery AE. The muscular dystrophies. Lancet 2002;359:687–695.

    Article  PubMed  CAS  Google Scholar 

  69. Suma H, Horii T, Isomura T, Buckberg GD. A new concept of ventricular restoration for nonischemic dilated cardiomyopathy. Eur J Cardiothorac Surg 2006;29:S207–S212.

    Article  PubMed  Google Scholar 

  70. Koyama T, Nishimura K, Soga Y, Unimonh O, Ueyama K, Komeda M. Importance of preserving the apex and placation of the base in left ventricular volume reduction surgery. J Thorac Cardiovasc Surg 2003;125:669–677.

    Article  PubMed  Google Scholar 

  71. Isomura T, Suma H, Horii T, Sato T, Kobashi T, Kanemitsu H, et al. Left ventricle restoration in patients with non-ischemic dilated cardiomyopathy: risk factors and predictors of outcome and change of mid-term ventricular function Eur J Cardiothorac Surg 2001;19:684–689.

    Article  PubMed  CAS  Google Scholar 

  72. Suma H, Tanabe H, Uejima T, Suzuki S, Horii T, Isomura T. Selected ventriculoplasty for idiopathic dilated cardiomyopathy with advanced congestive heart failure: midterm results and risk analysis. Eur J Cardiothorac Surg 2007;32:912–916.

    Article  PubMed  Google Scholar 

  73. Klein MD, Herman MV, Gorlin R. A hemodynamic study of left ventricular aneurysm. Circulation 1967;35:614–630.

    PubMed  CAS  Google Scholar 

  74. Athanasuleas C, Siler W, Buckberg GD. Myocardial protection during surgical ventricular restoration Eur J Cardiothorac Surg 2006;29:S231–S237.

    Article  PubMed  Google Scholar 

  75. Gaudron P, Eilles C, Kugler I, Ertl G. Progressive left ventricular dysfunction and remodeling after myocardial infarction: potential mechanisms and early predictors. Circulation 1993;87:755–763.

    PubMed  CAS  Google Scholar 

  76. Yamaguchi A, Ino T, Adachi H, Murata S, Kamio H, Okada M, et al. Left ventricular volume predicts postoperative course in patients with ischemic cardiomyopathy. Ann Thorac Surg 1998;65:434–438.

    Article  PubMed  CAS  Google Scholar 

  77. Migrino RQ, Young JB, Ellis SG, White HD, Lundergan CF, Miller DP, et al. End-systolic volume index at 90 to 180 minutes into reperfusion therapy for acute myocardial infarction is a strong predictor of early and late mortality: the Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries (GUSTO)-I angiographic investigators. Circulation 1997;96:116–121.

    PubMed  CAS  Google Scholar 

  78. Florea VG, Henein MY, Anker SD, Francis DP, Chambers JS, Ponikowski P, et al. Prognostic value of changes over time in exercise capacity and echocardiographic measurements in patients with chronic heart failure. Eur Heart J 2000;21:146–153.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Tadashi Isomura.

Additional information

This review was submitted at the invitation of the editorial committee.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Isomura, T. Surgical left ventricular reconstruction. Gen Thorac Cardiovasc Surg 59, 315–325 (2011). https://doi.org/10.1007/s11748-010-0742-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11748-010-0742-4

Key words

Navigation