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Clinical research of ulcerative colitis treated with herbal cake-partitioned moxibustion

  • Clinical Study
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Journal of Acupuncture and Tuina Science Aims and scope Submit manuscript

摘要

目的

观察隔药灸、 隔麸灸对溃疡性结肠炎(UC)患者症状的改善作用和对结肠黏膜TNF-α及其受体的影响。

方法

将67 例UC患者随机分为隔药灸组(35 例)和隔麸灸组(32 例), 对比观察两组患者症状的改善情况, 并采用免疫组织化学法观察两组结肠黏膜TNF-α及其受体的变化。

结果

隔药灸组在腹泻、 矢气、 神疲乏力、 里急后重、 腰酸症状的改善方面优于隔麸灸组; 隔药灸组结肠黏膜TNF-α、 TNF-αR1、 TNF-αR2 的表达均较治疗前显著下降, 隔麸灸组仅见TNF-αR1 较治疗前显著下降。

结论

艾灸对UC患者各项症状均有较好的改善作用, 在腹泻、 矢气等部分症状的改善方面, 隔药灸优于隔麸灸; 隔药灸能够下调结肠黏膜TNF-α、 TNF-αR1、 TNF-αR2 的表达, 隔麸灸仅能下调TNF-αR1的表达。

Abstract

Objective

To observe the effects of herbal cake-partitioned moxibustion and bran-partition moxibustion in improving symptoms of ulcerative colitis (UC) and the TNF-α and its receptor of colon mucosa.

Method

67 UC cases were randomly allocated into herbal cake-partition moxibustion group of 35 cases and bran-partitioned moxibustion group of 32 cases, to compare the improvement and detect the TNF-α and its receptor with immuno-histochemical method in both groups.

Result

Herbal cake-partitioned moxibustion is prior to bran-partitioned moxibustion in improving of diarrhea, flatus, lassitude, tenesmus and lumbar soreness; The expression of TNF-α,TNF-αR1, and TNF-αR2 are significantly decreased after treatment in herbal cake-partitioned moxibustion group, while in bran-partitioned moxibustion group only TNF-αR1 expression is significant decreased after treatment.

Conclusion

Moxibustion can well improve the syndromes of UC, Herbal cake-partitioned Moxibustion is prior to bran-partitioned moxibustion in the improvement of diarrhea and flatus; Herbal cake-partitioned moxibustion could down-regulate the expression of TNF-α,TNF-αR1, and TNF-αR2, while bran-partitioned moxibustion could only down-regulate the expression of TNF-αR1.

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References

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Authors and Affiliations

  1. Shanghai Research Institute of Acupuncture and Meridian, Shanghai, 200030, P. R. China

    Huan-gan Wu  (吴焕淦), Zheng Shi  (施征), Yi Zhu  (朱毅), Xiao-peng Ma  (马晓芃), Yi Yao  (姚怡), Yun-hua Cui  (崔云华), Tian-ping Zhao  (赵天平) & Hui-rong Liu  (刘慧荣)

Authors
  1. Huan-gan Wu  (吴焕淦)
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  2. Zheng Shi  (施征)
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  3. Yi Zhu  (朱毅)
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  4. Xiao-peng Ma  (马晓芃)
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  5. Yi Yao  (姚怡)
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  6. Yun-hua Cui  (崔云华)
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  7. Tian-ping Zhao  (赵天平)
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  8. Hui-rong Liu  (刘慧荣)
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Additional information

Author: WU Huan-gan (1956–), male, professor

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Wu, Hg., Shi, Z., Zhu, Y. et al. Clinical research of ulcerative colitis treated with herbal cake-partitioned moxibustion. J. Acupunct. Tuina. Sci. 7, 80–83 (2009). https://doi.org/10.1007/s11726-009-0080-1

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  • DOI: https://doi.org/10.1007/s11726-009-0080-1

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