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Measurements of the contact force from myenteric contractions on a solid bolus

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Abstract

The development of robotic capsule endoscopes (RCEs) is one avenue presently investigated by multiple research groups to minimize invasiveness and enhance outcomes of enteroscopic procedures. Understanding the biomechanical response of the small bowel to RCEs is needed for design optimization of these devices. In previous work, the authors developed, characterized, and tested the migrating motor complex force sensor (MFS), a novel sensor for quantifying the contact forces per unit of axial length exerted by the myenteron on a solid bolus. This work is a continuation, in which the MFS is used to quantify the contractile strength in the small intestine proximal, middle, and distal regions of five live porcine models. The MFSs are surgically implanted in a generally anesthetized animal, and force data from 5 min of dwell time are analyzed. The mean myenteric contact force from all porcine models and locations within the bowel is 1.9 ± 1.0 N cm−1. Examining the results based on the small bowel region shows a statistically significant strengthening trend in the contractile force from proximal to middle to distal with mean forces of 1.2 ± 0.5, 1.9 ± 0.9, and 2.3 ± 1.0 N cm−1, respectively (mean ± one standard deviation). Quantification of the contact force against a solid bolus provides developers of RCEs with a valuable, experimentally derived parameter of the intraluminal environment.

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Acknowledgments

The authors wish to acknowledge the Clinical and Translational Research Center at the University of Colorado at Boulder (CTRC) for assistance with the statistical analysis. This work was funded in part by a Junior Faculty Pilot Award from the Colorado Clinical and Translational Sciences Institute (CCTSI). This publication was supported by NIH/NCRR Colorado CTSI Grant no. UL1 RR025780. Its contents are the authors’ sole responsibility and do not necessarily represent official NIH view.

Conflict of interest

Drs. Schoen and Rentschler, and Mr. Terry have no conflicts of interest or financial ties to disclose. No benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript.

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Authors and Affiliations

  1. Department of Mechanical Engineering, University of Colorado at Boulder, 427 UCB, 1111 Engineering Drive, Boulder, CO, 80303-0427, USA

    Benjamin S. Terry & Mark E. Rentschler

  2. University of Colorado Hospital, Aurora, CO, USA

    Jonathan A. Schoen

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  1. Benjamin S. Terry
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  2. Jonathan A. Schoen
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  3. Mark E. Rentschler
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Correspondence to Benjamin S. Terry.

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Terry, B.S., Schoen, J.A. & Rentschler, M.E. Measurements of the contact force from myenteric contractions on a solid bolus. J Robotic Surg 7, 53–57 (2013). https://doi.org/10.1007/s11701-012-0346-3

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  • DOI: https://doi.org/10.1007/s11701-012-0346-3

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