Grundlagenforschung und translationale Forschung in der Onkologie konnten in den letzten Jahren eine Reihe von Biomarker identifizieren, die für Diagnostik, Staging, Prognoseabschätzung und als Ansatzpunkte für individualisierte Therapien potentiellen klinischen Wert haben. Einige dieser Marker sind bereits seit Jahren in die klinische Praxis eingeführt, andere werden derzeit im Rahmen wissenschaftlicher Programme an spezialisierten Krebszentren in der Praxis erprobt. Dieser Beitrag gibt einen Überblick klinisch etablierter Biomarker und einen Ausblick auf ausgewählte Kandidaten, die an der Schwelle zur breiten Anwendung stehen.
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Hoffmann, AC., Schuler, M. Biomarker in der Onkologie. best practice onkologie 3, 48–58 (2008). https://doi.org/10.1007/s11654-008-0092-1
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DOI: https://doi.org/10.1007/s11654-008-0092-1