Skip to main content
Log in

Summary

This study examined the association of pregnancy with urolithiasis and provided new insights into urolithiasis in pregnancy. A total of 462 subjects were studied from January 2004 to December 2009 in Foshan Maternal and Child Health Hospital, China. Among the 462 subjects, 162 cases of urolithiasis during pregnancy (UPG) were selected as the observation group, 150 cases of no urolithiasis during pregnancy (NUPG) served as pregnancy control group, and 150 cases of no pregnancy (NPG) at reproductive age who took part in physical examination were randomly assigned into non-pregnant control group. At the same time, the patients in observation group were divided into the following sub-groups: no symptomatic urinary calculus (NSUC) and symptomatic urinary calculus (SUC) groups; SUC group was further divided into surgical intervention (SI) and conservative management (CM) groups. The general information and the data of blood and urine were collected and compared among the groups. The results showed that the incidence of urinary calculi in pregnant women was lower than that in non-pregnant women, the formation of urinary stone was associated with the change of metabolism of protein and sugar in pregnant women, and the surgical intervention was a practicable alternative to treat the clinical intractable symptomatic urinary calculi in pregnancy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Cheriachan D, Arianayagam M, Rashid P. Symptomatic urinary stone disease in pregnancy. Aust N Z J Obstet Gynaecol, 2008,48(1):34–39

    Article  PubMed  Google Scholar 

  2. Srirangam SJ, Hickerton B, Van Cleynenbreugel B. Management of urinary calculi in pregnancy: a review. J Endourol, 2008,22(5):867–875

    Article  PubMed  Google Scholar 

  3. Biyani CS, Joyce AD. Urolithiasis in pregnancy. I: Pathophysiology, fetal considerations and diagnosis. BJU Int, 2002,89(8):811–818

    Article  PubMed  CAS  Google Scholar 

  4. Lifshitz DA, Lingeman JE. Ureteroscopy as a first-line intervention for ureteral calculi in pregnancy. J Endourol, 2002,16(1):19–22

    Article  PubMed  Google Scholar 

  5. Daudon M. Epidemiology of nephrolithiasis in France. Ann Urol (Paris), 2005,39(6):209–231

    CAS  Google Scholar 

  6. Ye ZQ, Deng YL, Dong C. Urinary tract stones. Beijing: People’s Medical Publishing House, 2003, 31–56

    Google Scholar 

  7. Charalambous S, Fotas A, Rizk DE. Urolithiasis in pregnancy. Int Urogynecol J Pelvic Floor Dysfunct, 2009, 20(9):1133–1136

    Article  PubMed  Google Scholar 

  8. Ross AE, Handa S, Lingeman JE, et al. Kidney stones during pregnancy: an investigation into stone composition. Urol Res, 2008,36(2):99–102

    Article  PubMed  Google Scholar 

  9. Smith AE, Kristensen C, Davis M, et al. An evaluation of the physicochemical risk for renal stone disease during pregnancy. Clin Nephrol, 2001,55(3):205–211

    PubMed  CAS  Google Scholar 

  10. Taylor EN, Curhan GC. Body size and 24-hour urine composition. Am J Kidney Dis, 2006,48(6):905–915

    Article  PubMed  CAS  Google Scholar 

  11. Shrotri KN, Morrison ID, Shrotri NC. Urological conditions in pregnancy: a diagnostic and therapeutic challenge. J Obstet Gynaecol, 2007,27(7):648–654

    Article  PubMed  CAS  Google Scholar 

  12. Travassos M, Amselem I, Filho NS, et al. Ureteroscopy in pregnant women for ureteral stone. J Endourol, 2009,23(3):405–407

    Article  PubMed  Google Scholar 

  13. Rana AM, Aquil S, Khawaja AM. Semirigid ureteroscopy and pneumatic lithotripsy as definitive management of obstructive ureteral calculi during pregnancy. Urology, 2009,73(5):964–967

    Article  PubMed  Google Scholar 

  14. Semins MJ, Trock BJ, Matlaga BR. The safety of ureteroscopy during pregnancy: a systematic review and meta-analysis. J Urol, 2009,181(1):139–143

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Zhangqun Ye  (叶章群).

Rights and permissions

Reprints and permissions

About this article

Cite this article

Liu, G., Wang, J., Li, J. et al. Urolithiasis in pregnancy: Survey in clinical epidemiology. J. Huazhong Univ. Sci. Technol. [Med. Sci.] 31, 226–230 (2011). https://doi.org/10.1007/s11596-011-0257-y

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11596-011-0257-y

Key words

Navigation