Abstract
The aim of this paper is to describe the intratumoural tissue components of solid lung tumours evidenced by macroscopic and/or microscopic examination of the autopsic or surgical specimen and visible on computed tomography (CT) without and with contrast material administration. Seven intratumoural tissue components can be identified both at CT and at pathology: (1) solid component, (2) haemorrhagic component, (3) coagulation necrosis, (4) liquefactive necrosis, (5) parenchymal consolidation, (6) diffuse peripheral component and (7) fibrotic component. Necrotic and haemorrhagic components are typically observed in malignant lesions, whereas solid and fibrotic components may be seen both in solid lung malignancies and in benign lesions.
Riassunto
Lo scopo di questa presentazione è descrivere le componenti tissutali intratumorali presenti nei tumori polmonari solidi che risultino evidenti all’analisi macroscopica e/o microscopica del campione patologico, autoptico oppure chirurgico, e che siano identificabili anche all’indagine tomografia computerizzata (TC) eseguita mediante metodica diretta e dopo la somministrazione di mezzo di contrasto. Sette distinte componenti tissutali intratumorali sono identificabili sulle immagini TC e sul reperto patologico: 1) componente solida; 2) componente emorragica; 3) necrosi coagulativa; 4) necrosi colliquativa; 5) addensamento parenchimale; 6) componente periferica diffusa; 7) componente fibrotica. Le componenti a carattere necrotico ed emorragico vengono osservate tipicamente nelle neoplasie maligne, mentre le componenti solide ed a carattere fibrotico possono essere osservate sia nei processi polmonari solidi a carattere maligno sia nelle lesioni benigne.
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Quaia, E., Baratella, E., Pizzolato, R. et al. Radiological-pathological correlation in intratumoural tissue components of solid lung tumours. Radiol med 114, 173–189 (2009). https://doi.org/10.1007/s11547-008-0354-6
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DOI: https://doi.org/10.1007/s11547-008-0354-6