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Health Related Quality of Life After Percutaneous Coronary Revascularisation in Patients with Previous Coronary Artery Bypass Grafts: A Two-Year Follow Up Study

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Abstract

Percutaneous coronary revascularisation [PCR] improves angina and health related quality of life [HRQOL] compared to standard medical therapy. It is unknown whether PCR has the same benefits for patients with a history of CABG. Over a period of 5 years, we assessed HRQOL of patients undergoing PCR using Part 1 of the Nottingham Health Profile [NHP] at baseline 3, 12 and 24 months. We compared HRQOL after PCR in 255 patients with CABG to 2680 without. There were more males [81.1% v 69.6% p = 0.002] and older patients [mean age 60.1 years v. 58.0 p = 0.03] in CABG group. Perceived HRQOL improved at 24 months for pain, energy and emotional reaction but the improvement was less in the CABG group. However, mean NHP scores at 24 months for those with CABG had returned to baseline levels for sleep [34.9] and for physical function was worse than at baseline [22.0 vs 30.7]. This relationship persisted after adjustment for male sex, history of previous MI and coronary stent usage. Patients with previous CABG had less improvement in HRQOL after PCR. Further work is needed to assess the benefits and cost effectiveness of PCR in these patients.

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Abbreviations

WHO:

World Health Organisation

HRQOL:

Health related quality of life

NHP:

Nottingham health profile questionnaire

CAD:

Coronary artery disease

PCR:

Percutaneous revascularisation

CABG:

Coronary artery bypass surgery

SF-36:

Short form- 36 questionnaire

SAQ:

Seattle angina questionnaire

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Correspondence to Azfar G. Zaman.

Appendix

Appendix

Table 4 Correlation of NHP values in patients with previous CABG after adjustment
Table 5 Effect size
Table 6 Floor and ceiling effect (Values in percentages)

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Viswanathan, G.N., Mayurathan, G., Hildreth, T. et al. Health Related Quality of Life After Percutaneous Coronary Revascularisation in Patients with Previous Coronary Artery Bypass Grafts: A Two-Year Follow Up Study. Applied Research Quality Life 6, 311–324 (2011). https://doi.org/10.1007/s11482-010-9130-6

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