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Dual Polarization Measurements in the Hybrid Plasmonic Biosensors

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Abstract

A novel affinity biosensor is proposed based on the hybrid plasmonic platform. The proposed biosensor benefits from the high sensitivity of the surface plasmon resonance (SPR), while at the same time, it is capable of performing measurements in both the TM and TE polarizations (p- and s-polarizations). Unlike the conventional SPR biosensors, the polarization diversity of the hybrid sensor allows for decoupling of the bulk index variations in the fluidic channels (due to variations in concentration, decomposition, temperature, and so on) from the surface properties of the attached molecules. Compatibility of the proposed hybrid plasmonic biosensor with standard Si-processing techniques and the simplicity of its design are other advantages of the sensor which makes its fabrication straightforward. The best figure of merit for the biosensor is defined based on the minimum detection limit and a genetic algorithm is used to optimize the device. A method of de-convolving the surface and bulk effects is also discussed.

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Notes

  1. Moreover, the bulk index of refraction (n b) can change due to compositional variations and temperature.

  2. The ability to provide the same output with measuring the same value of measurand illustrates the reliability of the measurements.

  3. Most conventional glass used in SiOG substrates is EAGLE XG™; however, the optical property of EAGLE XG™ is very similar to silica, and hence in our simulations, we have used silica as the substrate [34].

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Acknowledgments

We would like to acknowledge the use of computing resources from West Grid. This work was supported by the Natural Science and Engineering Research Council of Canada–Biopsys Network under grant no. 486537.

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Authors and Affiliations

  1. Department of Electrical and Computer Engineering, University of Toronto, Toronto, Ontario, M5S 3 G4, Canada

    F. Bahrami, M. Z. Alam, J. S. Aitchison & M. Mojahedi

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  1. F. Bahrami
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  2. M. Z. Alam
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  3. J. S. Aitchison
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  4. M. Mojahedi
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Correspondence to F. Bahrami.

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Bahrami, F., Alam, M.Z., Aitchison, J.S. et al. Dual Polarization Measurements in the Hybrid Plasmonic Biosensors. Plasmonics 8, 465–473 (2013). https://doi.org/10.1007/s11468-012-9411-z

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  • DOI: https://doi.org/10.1007/s11468-012-9411-z

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