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Acute Kidney Injury in the Setting of Knee Arthroplasty: A Case Report and Discussion Investigating Angiotensin-Converting Enzyme Inhibitors as the Culprit

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HSS Journal ®

Abstract

Total knee arthroplasty (TKA) has become the predominant treatment modality for severe degenerative joint disease. With recent advancements in surgical and anesthetic technique, patients with severe comorbidities are able to have this procedure; they would have been precluded from TKA only a matter of years ago. Although many studies have investigated risk factors and the causes of perioperative morbidity and mortality in the arthroplasty patient, few have linked risk factors with specific outcomes. We present a case report that illustrates the link between the use of angiotensin-converting enzyme inhibitors and the development of postoperative acute kidney injury. While this relationship has been extensively studied in cardiac and gastric bypass patient populations, it has never been examined in the setting of joint replacement.

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Authors and Affiliations

  1. Albany Medical Center, 43 New Scotland Ave, Albany, NY, 12208, USA

    Andrew J. Rosenbaum MD

  2. Division of Trauma and General Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

    Jason A. Luciano MD, MBA

  3. Department of Orthopaedic Surgery, Cooper University Hospital, Camden, NJ, USA

    Robert Marburger RN & Eric Hume MD

Authors
  1. Andrew J. Rosenbaum MD
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  2. Jason A. Luciano MD, MBA
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  3. Robert Marburger RN
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  4. Eric Hume MD
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Corresponding author

Correspondence to Andrew J. Rosenbaum MD.

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Each author certifies that he or she has no commercial associations (e.g., consultancies, stock ownership, equity interest, patent/licensing arrangements, etc.) that might pose a conflict of interest in connection with the submitted article.

Each author certifies that his or her institution has approved the reporting of this case and that all investigations were conducted in conformity with ethical principles of research.

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Rosenbaum, A.J., Luciano, J.A., Marburger, R. et al. Acute Kidney Injury in the Setting of Knee Arthroplasty: A Case Report and Discussion Investigating Angiotensin-Converting Enzyme Inhibitors as the Culprit. HSS Jrnl 7, 183–186 (2011). https://doi.org/10.1007/s11420-010-9189-5

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  • DOI: https://doi.org/10.1007/s11420-010-9189-5

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