Skip to main content

Advertisement

SpringerLink
Log in

Disposition Kinetics, Urinary Excretion and Dosage Regimen of Levofloxacin Formulation Following Single Intravenous Administration in Crossbred Calves

  • Short Communication
  • Published:
Veterinary Research Communications Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Abbreviations

ATCC:

American type culture collection

MIC:

minimum inhibitory concentration

References

  • Ahanger, A.A., Srivastava, A.K. and Raina, R., 2003. Disposition kinetics of enrofloxacin in crossbred calves. Journal of Veterinary Pharmacology and Toxicology, 3, 16–20

    Google Scholar 

  • Amsden, G.W., Graci, D.M., Cabelus, L.J. and Hejmanowski, L.G., 1999. A randomized, crossover design study of the pharmacology of extended-spectrum fluoroquinolones for pneumococcal infections. Chest, 116, 115–119

    Article  PubMed  CAS  Google Scholar 

  • Arret, B., Johnson, D.P. and Krishbaum, A., 1971. Outline of details for microbiological assay of antibiotics: second revision. Journal of Pharmaceutical Science, 60, 1689–1694

    Article  CAS  Google Scholar 

  • Atef, M., El-Gendi, A.Y., Aziza Amer, M.M. and El Aty, A.M., 2001. Some pharmacokinetic data for danofloxacin in healthy goats. Veterinary Research Communications, 25, 367–377

    Article  PubMed  CAS  Google Scholar 

  • Baggot, J.D., 1977. Principles of Drug Disposition in Domestic Animals, (W.B. Saunders, Philadelphia)

    Google Scholar 

  • Chien, S.C., Chow, A.T. and Rogge, M.C., 1997. Pharmacokinetics and safety of oral levofloxacin in human immunodeficiency virus-infected individuals receiving concomitant zidovudine. Antimicrobial Agents and Chemotherapy, 41, 1765–1769

    PubMed  CAS  Google Scholar 

  • Chulavatnatol, S., Chindavijak, B., Vibhagool, A., Wananukul, W., Sriapha, C. and Sirisangtragul, C., 1999. Pharmacokinetics of levofloxacin in healthy Thai male volunteers. Journal of the Medical Association of Thailand, 82, 1127–1135

    PubMed  CAS  Google Scholar 

  • Davis, R. and Bryson, H.M., 1994. Levofloxacin. A review of its antibacterial activity, pharmacokinetics and therapeutic efficacy. Drugs, 47, 677–700

    PubMed  CAS  Google Scholar 

  • Destache, C.J., Pakiz, C.B., Larsen, C., Owens, H. and Dash, A.K., 2001. Cerebrospinal fluid penetration and pharmacokinetics of levofloxacin in an experimental rabbit meningitis model. Journal of Antimicrobial Chemotherapy, 47, 611

    Article  PubMed  CAS  Google Scholar 

  • Edelstein, P.H., Edelstein, M.A., Lehr, K.H. and Ren, J., 1996. In vitro activity of levofloxacin against clinical isolates of Legionella spp, its pharmacokinetics in guinea pigs, and use in experimental Legionella pneumophila pneumonia. Journal of Antimicrobial Chemotherapy, 37, 117–126

    Article  PubMed  CAS  Google Scholar 

  • Gascon, A.R., Campo, E., Hernandez, R.M., Calvo, B., Errasti, J. and Pedraz Munoz, J.L., 2000. Pharmacokinetics of ofloxacin enantiomers after intravenous administration for antibiotic prophylaxis in biliary surgery. Journal of Clinical Pharmacology, 40, 869–874

    Article  PubMed  CAS  Google Scholar 

  • Gibaldi, M. and Perrier, D., 1982. Pharmacokinetics, (Marcel Dekker, New York)

    Google Scholar 

  • Ito, T., Yano, I., Masuda, S., Hashimoto, Y. and Inui, K., 1999. Distribution characteristics of levofloxacin and grepafloxacin in rat kidney. Pharmacological Research, 16, 534–539

    Article  CAS  Google Scholar 

  • Klesel, N., Geweniger, K.H., Koletzki, P., Isert, D., Limbert, M., Markus, A., Riess, G., Schramm, H. and Iyer, P., 1995. Chemotherapeutic activity of levofloxacin (HR 355, DR-3355) against systemic and localized infections in laboratory animals. Journal of Antimicrobial Chemotherapy, 35, 805–819

    Article  PubMed  CAS  Google Scholar 

  • Langtry, H.D. and Lamb, H.M., 1998. Levofloxacin : its use in infections of the respiratory tract, skin, soft tissues and urinary tract. Drugs, 56, 487–515

    Article  PubMed  CAS  Google Scholar 

  • Mochizuki, K., Ohkubo, S., Torisaki, M., Yamashita, Y., Tanahashi, T., Jin, Y., Okamura, Y. and Tanaka, M., 1994. Intraoccular penetration of oral levofloxacin in rabbits. Nippon Ganka Gakkai Zasshi, 98, 1085–1090

    PubMed  CAS  Google Scholar 

  • North, D.S., Fish, D.N. and Redington, J.J., 1998. Levofloxacin, a second-generation fluoroquinolone. Pharmacotherapy, 18, 915–935

    PubMed  CAS  Google Scholar 

  • Verho, M., Malerczyk, V., Damm, D. and Lehr, K.H., 1996. Pharmacokinetics of levofloxacin in comparison to the racemic mixture of ofloxacin in man. Drug Metabolism and Drug Interactions, 13, 57–67

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Pharmacology and Toxicology, College of Veterinary Science, Punjab Agricultural University, Ludhiana, India

    V. K. Dumka & A. K. Srivastava

Authors
  1. V. K. Dumka
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. K. Srivastava
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to V. K. Dumka.

Additional information

abbreviations for pharmacokinetic parameters are given in the footnotes of Table I

Rights and permissions

Reprints and permissions

About this article

Cite this article

Dumka, V.K., Srivastava, A.K. Disposition Kinetics, Urinary Excretion and Dosage Regimen of Levofloxacin Formulation Following Single Intravenous Administration in Crossbred Calves. Vet Res Commun 31, 873–879 (2007). https://doi.org/10.1007/s11259-007-0090-8

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11259-007-0090-8

Keywords

Search

Navigation