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Biological Activities of Extracts from Sumac (Rhus spp.): A Review

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Abstract

Sumac is the common name for a genus (Rhus) that contains over 250 individual species of flowering plants in the family Anacardiaceae. These plants are found in temperate and tropical regions worldwide, often grow in areas of marginal agricultural capacity, and have a long history of use by indigenous people for medicinal and other uses. The research efforts on sumac extracts to date indicate a promising potential for this plant family to provide renewable bioproducts with the following reported desirable bioactivities: antifibrogenic, antifungal, antiinflammatory, antimalarial, antimicrobial, antimutagenic, antioxidant, antithrombin, antitumorigenic, antiviral, cytotoxic, hypoglycaemic, and leukopenic. As well, the bioactive components can be extracted from the plant material using environmentally benign solvents that allow for both food and industrial end-uses. The favorable worldwide distribution of sumac also suggests that desirable bioproducts may be obtained at the source, with minimal transportation requirements from the source through processing to the end consumer. However, previous work has focussed in just a few members of this large plant family. In addition, not all of the species studied to date have been fully characterized for potential bioactive components and bioactivities. Thus, there remains a significant research gap spanning the range from lead chemical discovery through process development and optimization in order to better understand the full potential of the Rhus genus as part of global green technology based on bioproducts and bioprocesses research programs.

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References

  1. Clark JH (1999) Green chemistry: challenges and opportunities. Green Chem 1:1–8

    Article  CAS  Google Scholar 

  2. Clark JH (2006) Green chemistry: today (and tomorrow). Green Chem vol. 8. 17–21

    Article  CAS  Google Scholar 

  3. Clark JH, Budarin V, Deswarte FEI, Hardy JJE, Kerton FM, Hunt AJ, Luque R, Macquarrie DJ, Milkowski K, Rodriguez A, Samuel O, Tavener SJ, White RJ, Wilson AJ (2006) Green chemistry and the biorefinery: a partnership for a sustainable future. Green Chem 8:853–860

    Article  CAS  Google Scholar 

  4. Mestres R (2004) A brief structured view of green chemistry issues. Green Chem 6:G10–G12

    Article  Google Scholar 

  5. Tang SLY, Smith RL, Poliakoff M (2005) Principles of green chemistry. Green Chem 7:761–762

    Article  Google Scholar 

  6. Raston C (2005) Renewables and green chemistry. Green Chem 7:57

    Article  Google Scholar 

  7. Cacace JE, Mazza G (2006) Pressurized low polarity water extraction of lignans from whole flaxseed. J Food Engr 77:1087–1095

    Article  CAS  Google Scholar 

  8. Ignaciuk A, Vöhringer F, Ruijs A, van Ierland EC (2004) Competition between biomass and food production in the presence of energy policies: a partial equilibrium analysis. Energy Policy 34:1127–1138

    Article  Google Scholar 

  9. Berndes G (2006) The contribution of renewables to society. In: Dewulf J, Van Langenhove H (eds) Renewables-Based Technology. John Wiley & Sons, New York, NY, USA, pp. 3–18

    Google Scholar 

  10. Perlack RD (2006) Biomass as feedstock for a bioenergy and bioproducts industry: The technical feasability of a billion-ton annual supply. United States Department of Energy, Washington, DC, USA

    Google Scholar 

  11. USDA (2007) Germplasm Resources Information Network. Beltsville, MD, USA: United States Department of Agriculture, Agricultural Research Service. http://www.ars-grin.gov/npgs/aboutgrin.html

  12. Van Wyk BE, Wink M (2004) Medicinal plants of the world. Timber Press, Portland, OR, USA

    Google Scholar 

  13. Erichsen-Brown C (1989) Medicinal and Other Uses of North American Plants: A Historical Survey with Special Reference to the Eastern Indian Tribes. New York, NY, USA: Dover Publications

    Google Scholar 

  14. Sezik E, Tabata M, Yesilada E (1991) Traditional medicine in Turkey. 1. Folk medicine in northeast Anatolia. J Ethnopharmacol 35:191–196

    Article  CAS  Google Scholar 

  15. McCutcheon AR, Ellis SM, Hancock RE, Towers GH (1992) Antibiotic screening of medicinal plants of the British Columbian native peoples. J Ethnopharmacol 37:213–223

    Article  CAS  Google Scholar 

  16. McCutcheon AR, Ellis SM, Hancock RE, Towers GH (1994) Antifungal screening of medicinal plants of British Columbia native peoples. J Ethnopharmacol 44:157–169

    Article  CAS  Google Scholar 

  17. Saxena G, McCutcheon AR, Farmer S (1994) Antimicrobial constituents of Rhus glabra. J Ethnopharmacol 42:95–99

    Article  CAS  Google Scholar 

  18. Nimri LF, Meqdam MM, Alkofahi A (1999) Antibacterial activity of Jordanian medicinal plants. Pharm Biol 37:196–201

    Google Scholar 

  19. Nasar-Abbas SM, Halkman AK (2004) Inhibition of some foodborne bacteria by alcohol extract of sumac (Rhus coriaria L.). J Food Safety 24:257–267

    Article  Google Scholar 

  20. Adwan G, Abu-Shanab B, Adwan K, Abu-Shanab F (2006) Antibacterial effects of nutraceutical plants growing in Palestine on Pseudomonas aeruginosa. Turk J Biol 30:239–242

    Google Scholar 

  21. Fazeli MR, Amin G, Attari MMA, Ashtiani H, Jamalifar H, Samadi N (2007) Antimicrobial activities of Iranian sumac and avish-e shirazi (Zataria multiflora) against some food-borne bacteria. Food Contr 18:646–649

    Article  Google Scholar 

  22. Nasar-Abbas SM, Halkman AK (2004) Antimicrobial effect of water extract of sumac (Rhus coriaria L.) on the growth of some food borne bacteria including pathogens. Int J Food Microbiol 97:63–69

    Article  CAS  Google Scholar 

  23. Gulmez M, Oral N, Vatansever L (2006) The effect of water extract of sumac (Rhus coriaria L.) and lactic acid on decontamination and shelf life of raw broiler wings. Poultry Sci 85:1466–1471

    CAS  Google Scholar 

  24. Sagdic O, Ozcan M (2003) Antibacterial activity of Turkish spice hydrosols. Food Control 14:141–143

    Article  CAS  Google Scholar 

  25. Lin YM, Flavin MT, Schure R, Chen FC, Sidwell R, Barnard DL, Huffman JH, Kern ER (1999) Antiviral activities of bioflavonoids. Planta Med 65:120–125

    Article  CAS  Google Scholar 

  26. Ahmed MS, Galal AM, Ross SA, Ferreira D, Elsohly MA, Ibrahim AS, Mossa JS, El-Feraly FS (2001) A weakly antimalarial biflavanone from Rhus retinorrhoea. Phytochemistry 58:599–602

    Article  CAS  Google Scholar 

  27. Bagchi A, Sahai M, Ray AB (1985) Phenolic constituents of Rhus semialata leaves. Planta Med 51:467–468

    Article  CAS  Google Scholar 

  28. Pokorny J (1991) Natural antioxidants for food use. Trends Food Sci Technol 2:223–227

    Article  CAS  Google Scholar 

  29. Lee JC, Kim J, Lim KT, Yang MS, Jang YS (2001) Ethanol eluted extract of Rhus verniciflua Stokes showed both antioxidant and cytotoxic effects on mouse thymocytes depending on the dose and time of the treatment. J Biochem Mol Biol 34:250–258

    CAS  Google Scholar 

  30. Lee JC, Lim KT, Jang YS (2002) Identification of Rhus verniciflua Stokes compounds that exhibit free radical scavenging and anti-apoptotic properties. Biochem Biophys Acta 1570:181–191

    CAS  Google Scholar 

  31. Young DA (1976) Flavonoid chemistry and the phylogenetic relationships of the Julianiaceae. Syst Bot 1:149–162

    Article  Google Scholar 

  32. Keppler HH (1957) The isolation and constitution of molisacacidin, a new leucoanthocyanidin from the heartwood of Acacia mollisima. J Chem Soc 2721–2724

  33. Yasue M, Kato Y (1957) Components of wood of Rhus trichocarpa. Yakugaku Zasshi 77:1045–1047

    CAS  Google Scholar 

  34. Van Loo P, De Bruyn A, Verzelel M (1988) On the liquid chromatography and identification of the flavonoids present in the “sumach tannic acid” extracted from Rhus coriaria. Chromatographia 25:15–20

    Article  Google Scholar 

  35. Bate-Smith EC (1962) The phenolic constituents of plants and their taxonomic significance. I. Dicotyledons. J Linn Soc (Bot) 58:95–173

    Article  CAS  Google Scholar 

  36. Plouvier V (1970) Structure of flavone glycosides by nuclear magnetic resonance. Compounds of the genera Centaurea, Kerria, Rhus, and Scabiosa. CR Acad Sci (Paris) 270:2710–2713

    CAS  Google Scholar 

  37. Kitts DD, Lim KT (2001) Antitumorigenic and cytotoxic properties of an ethanol extract derived from Rhus verniciflua Stokes (RVS). J Toxicol Environ Health, Part A 64:357–371

    Article  CAS  Google Scholar 

  38. Park YS, Kim YS, Shin DH (2002) Antioxidative effects of ethanol extracts from Rhus vernicifera Stoke on yukwa (oil popped rice snack) base during storage. J Food Sci 67:2474–2479

    Article  CAS  Google Scholar 

  39. Ozcan M, Akgul A (1995) Antioxidant activity of extracts and essential oils from turkish spices on sunflower oil. Acta Alimentaria 24:81–90

    Google Scholar 

  40. Ozcan M (2003) Effect of sumach (Rhus coriaria L.) extracts on the oxidative stability of peanut oil. J Med Food 6:63–66

    Article  CAS  Google Scholar 

  41. Ozcan M (2003) Antioxidant activities of rosemary, sage, and sumac extracts and their combinations on stability of natural peanut oil. J Med Food 6:267–270

    Article  CAS  Google Scholar 

  42. Bozan B, Kosar M, Tunalier Z, Ozturk N, Baser KHC (2003) Antioxidant and free radical scavenging activities of Rhus coriaria and Cinnamomum cassia extracts. Acta Alimentaria 32:53–61

    Article  Google Scholar 

  43. Candan F (2003) Effect of Rhus coriaria L. (Anacardiaceae) on superoxide radical scavenging and xanthine oxidase activity. J Enzyme Inhib Med Chem 18:59–62

    Article  CAS  Google Scholar 

  44. Candan F, Sokmen A (2004) Effects of Rhus coriaria L. (Anacardiaceae) on lipid peroxidation and free radical scavenging activity. Phytother Res 18:84–86

    Article  Google Scholar 

  45. Bozkurt H (2006) Investigation of the effect of sumac extract and BHT addition on the quality of sucuk (Turkish dry-fermented sausage). J Sci Food Agric 86:849–856

    Article  CAS  Google Scholar 

  46. McCune LM, Johns T (2002) Antioxidant activity in medicinal plants associated with the symptoms of diabetes mellitus used by the Indigenous Peoples of the North American boreal forest. J Ethnopharmacol 82:197–205

    Article  Google Scholar 

  47. Wu PL, Lin SB, Huang CP, Chiou RYY (2002) Antioxidative and cytotoxic compounds extracted from the sap of Rhus succedanae. J Nat Prod 65:1719–1721

    Article  CAS  Google Scholar 

  48. Kuo SC, Teng CM, Lee LG, Chiu TH, Wu TS, Huang SC, Wu JB, Shieh TY, Chang RJ, Chou TC (1991) 6-Pentadecylsalicylic acid: An antithrombin component isolated from the stem of Rhus semialata var. roxburghii. Planta Med 57:247–249

    Article  CAS  Google Scholar 

  49. Lee SH, Nan JX, Zhao YZ, Woo SW, Park EJ, Kang TH, Seo GS, Kim YC, Sohn DH (2003) The chalcone butein from Rhus verniciflua shows antifibrogenic activity. Planta Med 69:990–994

    Article  CAS  Google Scholar 

  50. Fourie TG, Snyckers FO (1984) A flavone with antiinflammatory activity from the roots of Rhus undulate. J Nat Prod 47:1057–1058

    Article  CAS  Google Scholar 

  51. Giancarlo S, Rosa ML, Nadjafi F, Francesco M (2006) Hypoglycaemic activity of two spices extracts: Rhus coriaria L. and Bunium persicum Boiss. Nat Prod Res 20:882–886

    Article  CAS  Google Scholar 

  52. Park KY, Jung GO, Lee KT, Choi J, Choi MY, Kim GT, Jung HJ, Park HJ (2004) Antimutagenic activity of flavonoids from the heartwood of Rhus verniciflua. J Ethnopharmacol 90:73–79

    Article  CAS  Google Scholar 

  53. Oshima R, Kumanotani J (1984) Structural studies of plant gum from sap of the lac tree, Rhus vernicifera. Carb Res 127:43–57

    Article  CAS  Google Scholar 

  54. Du Y, Kong Z, Li H (1994) Studies on separation and structure of lacquer polysaccharide. Acta Polymerica Sinica 3:301–306

    Google Scholar 

  55. Du Y, Yang J, Kong Z, Xiao L (1999) Structure and bioactivities of lacquer polysaccharides from Chinese lac trees of wild species and cultispecies. Chem J Chin Univ 20:399–402

    CAS  Google Scholar 

  56. Yang J, Du Y (2003) Sulfation of Chinese lacquer polysaccharides in different solvents. Carb Polym 52:405–410

    Article  CAS  Google Scholar 

  57. Son YO, Lee KY, Lee JC, Jang HS, Kim JG, Jeon YM, Jang YS (2005) Selective antiproliferative and apoptotic effects of flavonoids purified from Rhus verniciflua Stokes on normal versus transformed hepatic cell lines. Toxicol Lett 155:115–125

    Article  CAS  Google Scholar 

  58. Lee JC, Lee KY, Kim J, Na CS, Jung NC, Chung GH, Jang YS (2004) Extract from Rhus verniciflua Stokes is capable of inhibiting the growth of human lymphoma cells. Food Chem Toxicol 42:1383–1388

    Article  CAS  Google Scholar 

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Acknowledgements

We thank the Natural Sciences and Engineering Research Council (NSERC) of Canada for financial support.

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Correspondence to G. Mazza.

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Rayne, S., Mazza, G. Biological Activities of Extracts from Sumac (Rhus spp.): A Review. Plant Foods Hum Nutr 62, 165–175 (2007). https://doi.org/10.1007/s11130-007-0058-4

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