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Incidence, admission and case-fatality of acute myocardial infarction: weekend versus weekday in a Japanese population: 16-year results from Takashima AMI Registry (1988–2003)

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Abstract

For acute myocardial infarction (AMI), “weekend” has been associated with higher incidence, admission, and fatality. But, very few studies in this regard are available in Japan. Day of the week variation in AMI was examined using an entire community covering 16-year AMI registration data from Japan. Data were obtained from the Takashima AMI Registry, which covers a stable population of approximately 55,000 in central Japan. There were 379 registered first ever AMI cases with 121 fatal events within 28 days of onset during 1988–2003. We divided the days into two groups: ‘Weekend’ (Saturday and Sunday) and ‘Weekdays’ (Monday to Friday). The incidence rate (per 100,000 person-year), admission rate (per 1,000 days) and 28-day case-fatality rates (per 100 events) as well as corresponding rate ratios were calculated with 95% confidence intervals. The distribution of the day of the week for onset, admission and fatality for all subjects was fairly random in our study population; incidence (χ 2 test, P = 0.8), admission (χ 2 test, P = 0.9) and case-fatality (χ 2 test, P = 0.8). The incidence, admission, and case-fatality rates were similar for the 2 day-groups. The incidence rate ratio 1.06 (95% CI: 0.9–1.3), admission ratio 1.03 (95% CI: 0.8–1.3), and case-fatality ratio 1.18 (95% CI: 0.7–1.9) showed no significant risk difference between weekend and weekday. After various adjustments, hazard ratio for weekend AMI in reference to weekday AMI was 1.07 (95% CI: 0.5–2.1). There were no obvious differences in occurrence, hospital admission and acute outcome for AMI patients in the weekday or weekend.

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Abbreviations

AMI:

Acute myocardial infarction

CI:

Confidence interval

WHO-MONICA:

World Health Organization Monitoring Trends and Determinants in Cardiovascular Disease

ECG:

Electrocardiograph

HR:

Hazard ratio

CHD:

Coronary heart disease

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Acknowledgments

This study was supported in part by grants from The Research on Cardiovascular Disease (3A-1, 6A-5 and 7A-2) and The Comprehensive Research on Cardiovascular and Life Style Related Diseases (H18-CVD-Ippan-029) of the Ministry of Health and Welfare, and from the Grants-in-Aid Scientific Research (C-213670361 and B-17390186) of Ministry of Education, Culture, Sports, Science and Technology. Tanvir Chowdhury Turin is supported by the fellowship and Research Grants-In-Aid (P-20.08124) from the Japan Society for the Promotion of Science (JSPS).

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Authors and Affiliations

  1. Department of Health Science, Shiga University of Medical Science, Seta Tsukinowa-cho, Otsu, Shiga, 520-2192, Japan

    Tanvir Chowdhury Turin, Yoshikuni Kita, Nahid Rumana & Hirotsugu Ueshima

  2. Takashima General Hospital, Takashima, Shiga, Japan

    Hideki Sugihara

  3. Makino Hospital, Takashima, Shiga, Japan

    Yutaka Morita

  4. Otsu Red Cross Hospital, Otsu, Shiga, Japan

    Nobuyoshi Tomioka

  5. The First Institute for Health Promotion and Health Care, Tokyo, Japan

    Akira Okayama

  6. Kyoto Women’s University, Kyoto, Japan

    Yasuyuki Nakamura

Authors
  1. Tanvir Chowdhury Turin
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  2. Yoshikuni Kita
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  3. Nahid Rumana
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  4. Hideki Sugihara
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  5. Yutaka Morita
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  6. Nobuyoshi Tomioka
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  7. Akira Okayama
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  8. Yasuyuki Nakamura
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  9. Hirotsugu Ueshima
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Correspondence to Tanvir Chowdhury Turin.

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Turin, T.C., Kita, Y., Rumana, N. et al. Incidence, admission and case-fatality of acute myocardial infarction: weekend versus weekday in a Japanese population: 16-year results from Takashima AMI Registry (1988–2003). Eur J Epidemiol 24, 93–100 (2009). https://doi.org/10.1007/s10654-008-9308-5

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  • DOI: https://doi.org/10.1007/s10654-008-9308-5

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