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Étude botanique et exploration de l’activité antifongique de Morinda morindoides (Baker) Milne-Redh. sur la croissance in vitro de Cryptococcus neoformans

Botanical survey and in vitro exploration of antifungical activity of Morinda morindoides (Baker) Milne-Redh. on the growth of Cryptococcus neoformans

  • Article Original
  • Pharmacognosie
  • Published:
Phytothérapie

Résumé

Morinda morindoides est une plante qui est citée de façon récurrente dans plusieurs prescriptions thérapeutiques. Afin de mieux connaître cette plante et de pouvoir l’identifier sur le terrain, nous avons, dans cette étude, fait sa description botanique suivie d’une exploration de son activité antifongique. Il ressort de cette étude que Morinda morindoides (Rubiaceae) est une espèce guinéo-congolaise qui se retrouve dans les lisières des forêts. C’est une liane grimpante avec des feuilles opposées et possédant des fruits bosselés. Cette plante possède une activité antifongique in vitro sur Cryptococcus neoformans. Parmi les extraits testés, la fraction 1 (F1) (CMF = 0,78 mg/ml; CI50 = 0,08 ± 0,02 mg/ml) est la plus active.

Abstract

Morinda morindoides is a plant that is mentioned in a recurrent way in several therapeutic prescriptions. In order to know this plant and be able to identify it on the land, we have, in this study, made its botanical description followed of an exploration of its antifungal activity. It is evident from this study that Morinda morindoides (Rubiaceae) is a guineo-congolese species that meets in the borders of the forests. It is a trailing liana with opposite leaves and propertied of the bumpy fruits that yellow to maturity. This plant possesses an in vitro antifungal activity on Cryptococ-cus neoformans. Among the tested extracts, the fraction 1 (F1) [MFC = 0.78 mg/ml; IC50 = 0.08 ± 0.02 mg/ml] is the most active.

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Authors and Affiliations

  1. Laboratoire de pharmacodynamie biochimique, UFR biosciences, universityé de Cocody, 22 BP 582, Abidjan 22, Côte-d’Ivoire

    I. Bagre, C. Bahi, K. Ouattara, A. J. Djaman, A. Coulibaly & J. D. N’Guessan

  2. Laboratoire de botanique, UFR biosciences, universityé de Cocody, 22 BP 582, Abidjan 22, Côte-d’Ivoire

    N. Zirihi Guede

  3. Institut Pasteur de Côte-d’Ivoire, 01 BP 490, Abidjan 01, Côte-d’Ivoire

    A. J. Djaman

Authors
  1. I. Bagre
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  2. C. Bahi
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  3. K. Ouattara
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  4. N. Zirihi Guede
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  5. A. J. Djaman
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  6. A. Coulibaly
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  7. J. D. N’Guessan
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Correspondence to I. Bagre.

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Bagre, I., Bahi, C., Ouattara, K. et al. Étude botanique et exploration de l’activité antifongique de Morinda morindoides (Baker) Milne-Redh. sur la croissance in vitro de Cryptococcus neoformans . Phytothérapie 9, 136–141 (2011). https://doi.org/10.1007/s10298-011-0612-y

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  • DOI: https://doi.org/10.1007/s10298-011-0612-y

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