Références
Albain KS, Barlow WE, Shak S, et al. (2010) Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial. Lancet Oncol 11(1): 55–65
Al-Hajj M, Wicha MS, Benito-Hernandez A, et al. (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100(7): 3983–3988
Azim Jr HA, Michiels S, Bedard PL, et al. (2012) Biology of breast cancer diagnosed in young women: pooled gene expression analysis from 3,522 patients. Ann Oncol 23(Suppl 2): ii19 (140-PR)
Barton S, Zabaglo L, A’Hern R, et al. (2012) Assessment of the contribution of the IHC4+C score to decision-making in clinical practice in early breast cancer. Br J Cancer 106(11): 1760–1765
Beresford MJ, Stott D, Makris A (2008) Assessment of clinical response after two cycles of primary chemotherapy in breast cancer. Breast Cancer Res Treat 109(2): 337–342
Berruti A, Generali D, Kaufmann M, et al. (2011) International expert consensus on primary systemic therapy in the management of early breast cancer: highlights of the Fourth Symposium on Primary Systemic Therapy in the Management of Operable Breast Cancer, Cremona, Italy (2010). J Natl Cancer Inst Monogr (43): 147–151
Blohmer JU, Rezai M, Kummel S, et al. (2013) Using the 21-gene assay to guide adjuvant chemotherapy decision-making in early-stage breast cancer: a cost-effectiveness evaluation in the German setting. J Med Econ 16(1): 30–40
Bullwinkel J, Baron-Luhr B, Ludemann A, et al. (2006) Ki-67 protein is associated with ribosomal RNA transcription in quiescent and proliferating cells. J Cell Physiol 206(3): 624–635
Buyse M, Loi S, van’t Veer L, et al. (2006) Validation and clinical utility of a 70-gene prognostic signature for women with node-negative breast cancer. J Natl Cancer Inst 98(17): 1183–1192
Cheang MC, Chia SK, Voduc D, et al. (2009) Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst 101(10): 736–750
Coudert B, Asselain B, Campone M, et al. (2012) Extended benefit from sequential administration of docetaxel after standard fluorouracil, epirubicin, and cyclophosphamide regimen for node-positive breast cancer: the 8-year follow-up results of the UNICANCER-PACS01 trial. Oncologist 17(7): 900–909
Cronin M, Sangli C, Liu ML, et al. (2007) Analytical validation of the Oncotype DX genomic diagnostic test for recurrence prognosis and therapeutic response prediction in node-negative, estrogen receptor-positive breast cancer. Clin Chem 53(6): 1084–1091
Cuzick J, Dowsett M, Pineda S, et al. (2011) Prognostic value of a combined estrogen receptor, progesterone receptor, Ki67, and human epidermal growth factor receptor 2 immunohistochemical score and comparison with the genomic health recurrence score in early breast cancer. J Clin Oncol 29(32): 4273–4278
Daidone MG, Silvestrini R (2001) Prognostic and predictive role of proliferation indices in adjuvant therapy of breast cancer. J Natl Cancer Inst Monogr 30: 27–35
Ding L, Ellis MJ, Li S, et al. (2010) Genome remodelling in a basal-like breast cancer metastasis and xenograft. Nature 464(7291): 999–1005
Dowsett M, Nielsen TO, A’Hern R, et al. (2011) Assessment of Ki67 in breast cancer: recommendations from the international Ki67 in breast cancer working group. J Natl Cancer Inst 103(22): 1656–1664
Dowsett M, Smith IE, Ebbs SR, et al. (2007) Prognostic value of Ki67 expression after short-term presurgical endocrine therapy for primary breast cancer. J Natl Cancer Inst 99(2): 167–170
Dumontet C, Krajewska M, Treilleux I, et al. (2010) BCIRG 001 molecular analysis: prognostic factors in node-positive breast cancer patients receiving adjuvant chemotherapy. Clin Cancer Res 16(15): 3988–3997
Ellis MJ, Tao Y, Luo J, et al. (2008) Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics. J Natl Cancer Inst 100(19): 1380–1388
Filipits M, Rudas M, Jakesz R, et al. (2011) A new molecular predictor of distant recurrence in ER-positive, HER2-negative breast cancer adds independent information to conventional clinical risk factors. Clin Cancer Res 17(18): 6012–6020
Gerdes J, Schwab U, Lemke H, Stein H (1983) Production of a mouse monoclonal antibody reactive with a human nuclear antigen associated with cell proliferation. Int J Cancer 31(1): 13–20
Gerlinger M, Rowan A, Horswell S, et al. (2012) Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. N Engl J Med 366(10): 883–892
Gokmen-Polar Y, Badve S (2012) Molecular profiling assays in breast cancer: are we ready for prime time? Oncology (Williston Park) 26(4): 350–357, 61
Goldhirsch A, Wood WC, Coates AS, et al. (2011) Strategies for subtypes —ealing with the diversity of breast cancer: highlights of the St. Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011. Ann Oncol 22(8): 1736–1747
Guiu S, Michiels S, Andre F, et al. (2012) Molecular subclasses of breast cancer: how do we define them? The IMPAKT 2012 Working Group Statement. Ann Oncol 23(12): 2997–3006
Habashy HO, Powe DG, Abdel-Fatah TM, et al. (2012) A review of the biological and clinical characteristics of luminal-like oestrogen receptor-positive breast cancer. Histopathology 60(6): 854–863
Hall PS, McCabe C, Stein RC, Cameron D (2012) Economic evaluation of genomic test-directed chemotherapy for early-stage lymph node-positive breast cancer. J Natl Cancer Inst 104(1): 56–66
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144(5): 646–674
Harris L, Fritsche H, Mennel R, et al. (2007) American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. J Clin Oncol 25(33): 5287–5312
Henry LR, Stojadinovic A, Swain SM, et al. (2009) The influence of a gene expression profile on breast cancer decisions. J Surg Oncol 99(6): 319–323
Heppner G (1984) Tumor heterogeneity. Cancer Res 44: 2259–2265
Hugh J, Hanson J, Cheang MC, et al. (2009) Breast cancer subtypes and response to docetaxel in node-positive breast cancer: use of an immunohistochemical definition in the BCIRG 001 trial. J Clin Oncol 27(8): 1168–1176
Jankowitz RC, Cooper K, Erlander MG, et al. (2011) Prognostic utility of the breast cancer index and comparison to adjuvant! Online in a clinical case series of early breast cancer. Breast Cancer Res 13(5): R98
Jerevall PL, Ma XJ, Li H, et al. (2011) Prognostic utility of HOXB13:IL17BR and molecular grade index in early-stage breast cancer patients from the Stockholm trial. Br J Cancer 104(11): 1762–1769
Jones RL, Salter J, A’Hern R, et al. (2009) The prognostic significance of Ki67 before and after neoadjuvant chemotherapy in breast cancer. Breast Cancer Res Treat 116(1): 53–68
Kelly CM, Warner E, Tsoi DT, et al. (2010) Review of the clinical studies using the 21-gene assay. Oncologist 15(5): 447–456
Klang SH, Hammerman A, Liebermann N, et al. (2010) Economic implications of 21-gene breast cancer risk assay from the perspective of an Israeli-managed health care organization. Value Health 13(4): 381–387
Knauer M, Cardoso F, Wesseling J, et al. (2010) Identification of a low-risk subgroup of HER-2-positive breast cancer by the 70-gene prognosis signature. Br J Cancer 103(12): 1788–1793
Kondo M, Hoshi SL, Yamanaka T, et al. (2011) Economic evaluation of the 21-gene signature (Oncotype DX) in lymph node-negative/positive, hormone receptor-positive early-stage breast cancer based on Japanese validation study (JBCRG-TR03). Breast Cancer Res Treat 127(3): 739–749
Kronenwett R, Bohmann K, Prinzler J, et al. (2012) Decentral gene expression analysis: analytical validation of the Endopredict_genomic multianalyte breast cancer prognosis test. BMC Cancer 12: 456
Laas E, Vataire AL, Aballea S, et al. (2012) Evaluation of the costs and resource use associated with adjuvant chemotherapy for breast cancer in France. J Med Econ 15(6): 1167–1175
Lamond NW, Skedgel C, Rayson D, et al. (2012) Cost-utility of the 21-gene recurrence score assay in node-negative and node-positive breast cancer. Breast Cancer Res Treat 133(3): 1115–1123
Lo SS, Mumby PB, Norton J, et al. (2010) Prospective multicenter study of the impact of the 21-gene recurrence score assay on medical oncologist and patient adjuvant breast cancer treatment selection. J Clin Oncol 28(10): 1671–1676
Loi S, Haibe-Kains B, Desmedt C, et al. (2007) Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade. J Clin Oncol 25(10): 1239–1246
Luporsi E, Andre F, Spyratos F, et al. (2012) Ki-67: level of evidence and methodological considerations for its role in the clinical management of breast cancer: analytical and critical review. Breast Cancer Res Treat 132(3): 895–915
Mackey JR, Martin M, Pienkowski T, et al. (2013) Adjuvant docetaxel, doxorubicin, and cyclophosphamide in node-positive breast cancer: 10-year follow-up of the phase 3 randomised BCIRG 001 trial. Lancet Oncol 14(1): 72–80
Metzger Filho O, Ignatiadis M, Sotiriou C (2011) Genomic Grade Index: an important tool for assessing breast cancer tumor grade and prognosis. Crit Rev Oncol Hematol 77(1): 20–29
Mook S, Schmidt MK, Viale G, et al. (2009) The 70-gene prognosis-signature predicts disease outcome in breast cancer patients with 1–3 positive lymph nodes in an independent validation study. Breast Cancer Res Treat 116(2): 295–302
Navin N, Kendall J, Troge J, et al. (2011) Tumour evolution inferred by single-cell sequencing. Nature 472(7341): 90–94
Nielsen TO, Parker JS, Leung S, et al. (2010) A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer. Clin Cancer Res 16(21): 5222–5232
Nik-Zainal S, Van Loo P, Wedge DC, et al. (2012) The life history of 21 breast cancers. Cell 149(5): 994–1007
Paik S, Shak S, Tang G, et al. (2004) A multigene assay to predict recurrence of tamoxifen-treated, node-negative breast cancer. N Engl J Med 351(27): 2817–2826
Paik S, Tang G, Shak S, et al. (2006) Gene expression and benefit of chemotherapy in women with node-negative, estrogen receptor-positive breast cancer. J Clin Oncol 24(23): 3726–3734
Parker JS, Mullins M, Cheang MC, et al. (2009) Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol 27(8): 1160–1167
Penault-Llorca F, Goubar A, Raoelfils I, et al. (2012) Interpathologists discrepancies in Ki67 assessment in the PACS01 trial: an independent prognosis factor. J Clin Oncol 30(Suppl); abstr 543
Penault-Llorca F, Andre F, Sagan C, et al. (2009) Ki67 expression and docetaxel efficacy in patients with estrogen receptor-positive breast cancer. J Clin Oncol 27(17): 2809–2815
Perou CM, Jeffrey SS, van de Rijn M, et al. (1999) Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci USA 96(16): 9212–9217
Perou CM, Sorlie T, Eisen MB, et al. (2000) Molecular portraits of human breast tumours. Nature 406(6797): 747–752
Regan MM, Neven P, Giobbie-Hurder A, et al. (2011) Assessment of letrozole and tamoxifen alone and in sequence for postmenopausal women with steroid hormone receptor-positive breast cancer: the BIG 1–98 randomised clinical trial at 8.1 years median follow-up. Lancet Oncol 12(12): 1101–1108
Sheri A, Dowsett M (2012) Developments in Ki67 and other biomarkers for treatment decision-making in breast cancer. Ann Oncol 23(Suppl 10): x219–x227
Simon RM, Paik S, Hayes DF (2009) Use of archived specimens in evaluation of prognostic and predictive biomarkers. J Natl Cancer Inst 101(21): 1446–1452
Sorlie T, Perou CM, Tibshirani R, et al. (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98(19): 10869–10874
Sotiriou C, Neo SY, McShane LM, et al. (2003) Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci USA 100(18): 10393–10398
Sotiriou C, Wirapati P, Loi S, et al. (2006) Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis. J Natl Cancer Inst 98(4): 262–272
Stadler ZK, Come SE (2009) Review of gene-expression profiling and its clinical use in breast cancer. Crit Rev Oncol Hematol 69(1): 1–11
Stephens PJ, Tarpey PS, Davies H, et al. (2012) The landscape of cancer genes and mutational processes in breast cancer. Nature 486(7403): 400–404
Tang G, Cuzick J, Costantino JP, et al. (2011) Risk of recurrence and chemotherapy benefit for patients with node-negative, estrogen receptor-positive breast cancer: recurrence score alone and integrated with pathologic and clinical factors. J Clin Oncol 29(33): 4365–4372
Teutsch SM, Bradley LA, Palomaki GE, et al. (2009) The Evaluation of Genomic Applications in Practice and Prevention (EGAPP) Initiative: methods of the EGAPP Working Group. Genet Med 11(1): 3–14
Urruticoechea A, Smith IE, Dowsett M (2005) Proliferation marker Ki-67 in early breast cancer. J Clin Oncol 23(28): 7212–7220
van de Vijver MJ, He YD, van’t Veer LJ, et al. (2002) A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 347(25): 1999–2009
van Diest PJ, van der Wall E, Baak JP (2004) Prognostic value of proliferation in invasive breast cancer: a review. J Clin Pathol 57(7): 675–681
van’t Veer LJ, Dai H, van de Vijver MJ, et al. (2002) Gene expression profiling predicts clinical outcome of breast cancer. Nature 415(6871): 530–536
Varga Z, Diebold J, Dommann-Scherrer C, et al. (2012) How reliable is Ki-67 immunohistochemistry in grade II breast carcinomas? A QA study of the Swiss Working Group of Breast- and Gynecopathologists. PLoS ONE 7(5): e37379
Vataire AL, Laas E, Aballea S, et al. (2012) Cost-effectiveness of a chemotherapy predictive test. [Article in French] Bull Cancer 99(10): 907–914
Viale G, Giobbie-Hurder A, Regan MM, et al. (2008) Prognostic and predictive value of centrally reviewed Ki-67 labelling index in postmenopausal women with endocrine-responsive breast cancer: results from Breast International Group Trial 1–98 comparing adjuvant tamoxifen with letrozole. J Clin Oncol 26(34): 5569–5575
Viale G, Regan MM, Mastropasqua MG, et al. (2008) Predictive value of tumor Ki-67 expression in two randomized trials of adjuvant chemoendocrine therapy for node-negative breast cancer. J Natl Cancer Inst 100(3): 207–212
Visvader JE, Lindeman GJ (2008) Cancer stem cells in solid tumours: accumulating evidence and unresolved questions. Nat Rev Cancer 8(10): 755–768
von Minckwitz G, Untch M, Loibl S (2013) Update on neoadjuvant/preoperative therapy of breast cancer: experiences from the German Breast Group. Curr Opin Obstet Gynecol 25(1): 66–73
Weigel MT, Dowsett M (2010) Current and emerging biomarkers in breast cancer: prognosis and prediction. Endocr Relat Cancer 17(4): R245–R262
Yang M, Rajan S, Issa AM (2012) Cost effectiveness of gene expression profiling for early-stage breast cancer: a decision-analytic model. Cancer 118(20): 5163–5170
Yerushalmi R, Woods R, Ravdin PM, et al. (2010) Ki67 in breast cancer: prognostic and predictive potential. Lancet Oncol 11(2): 174–183
Références électroniques
Collège des économistes de la santé (2008) Guide méthodologique pour la mise en place d’une analyse d’impact budgétaire. Available from: http://www.ces-asso.org/docs/Rapport_AIB.pdf
Haute Autorité de santé (2011) Choix méethodologiques pour l’éevaluation économique à la HAS. Available from: http://www.has-sante.fr/portail/upload/docs/application/pdf/2011-11/guide_methodo_vf.pdf
Orphanet. Hémoglobinurie paroxystique nocturne 2012. Available from: http://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=FR&Expert=447.
SOLIRIS 300MG/30ML SOL INJ FL 30ML —Monographie specialité. 2012. Available from: http://www.theriaque.org/apps/monographie/index.php?type=SP&id=21952&info=ADMIN
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André, F., Delaloge, S., Guinebretière, J.M. et al. Prolifération des cancers du sein et biomarqueurs décisionnels en pratique RPC (RPC 2013). Oncologie 15, 594–604 (2013). https://doi.org/10.1007/s10269-013-2341-3
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DOI: https://doi.org/10.1007/s10269-013-2341-3