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A report from Fukushima: an assessment of bone health in an area affected by the Fukushima nuclear plant incident

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Abstract

Bone health was assessed for inhabitants of an area affected by the Fukushima nuclear plant incident. Osteoporotic patients, who had been treated with active vitamin D3 and/or bisphosphonate at Soma Central Hospital before the Fukushima incident, were enrolled. Changes in bone turnover markers and bone mineral density were retrospectively analyzed. Serum levels of a bone resorption marker, serum type I collagen cross-linked N-telopeptide were decreased in all the treated groups, whereas those of a bone formation marker, bone-specific alkaline phosphatase, were increased. Accordingly, bone mineral density, estimated by dual-energy X-ray absorptiometry, was increased in the lumbar spine of all groups, but bone mass increase in the proximal femur was detected only in the group treated with the two agents in combination. From the degree of these parameter changes, the antiosteoporotic treatments looked effective and were equivalent to the expected potency of past observations. At this stage, the present study implies that the Fukushima nuclear incident did not bring an acute risk to bone health in the affected areas.

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Conflict of interest

The authors declare no conflict of interest.

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Authors and Affiliations

  1. Department of Orthopaedic Surgery, Soma Central Hospital, 3-5-18 Okinouchi, Soma, Fukushima, 976-0016, Japan

    Takeaki Ishii

  2. Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

    Takeaki Ishii & Yukihide Iwamoto

  3. Department of Orthopaedic Surgery, JR Sendai Hospital, Sendai, Japan

    Kazuo Ito

  4. Department of Radiation Protection, Soma Central Hospital, Soma, Japan

    Shigeaki Kato & Masaharu Tsubokura

  5. Department of Internal Medicine, Soma Central Hospital, Soma, Japan

    Yasutoshi Saito

  6. Division of Social Communication System for Advanced Clinical Research, The Institute of Medical Science, University of Tokyo, Tokyo, Japan

    Masaharu Tsubokura

  7. MRC-HPA Centre for Environment and Health, Imperial College London, London, UK

    Sae Ochi

  8. Seisa University, Yokohama, Japan

    Sae Ochi

Authors
  1. Takeaki Ishii
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  2. Kazuo Ito
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  3. Shigeaki Kato
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  4. Masaharu Tsubokura
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  5. Sae Ochi
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  6. Yukihide Iwamoto
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  7. Yasutoshi Saito
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Correspondence to Takeaki Ishii.

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Ishii, T., Ito, K., Kato, S. et al. A report from Fukushima: an assessment of bone health in an area affected by the Fukushima nuclear plant incident. J Bone Miner Metab 31, 613–617 (2013). https://doi.org/10.1007/s00774-013-0482-5

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  • DOI: https://doi.org/10.1007/s00774-013-0482-5

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