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Human diseases related to aluminium overload

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Abstract

In this paper attention is devoted to the role of aluminium in osteodistrophy and dialysis dementia. In fact, these diseases, in spite of the actions that have drastically reduced their occurrence, have so far constituted a cause of great medical concern. As a preliminary point, some aspects concerning the solution chemistry of aluminium are considered, then the medical problems are described and finally the chelation therapy of aluminium overload, giving some insight on the chelators recently proposed.

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Authors and Affiliations

  1. Dipartimento di Scienze Chimiche, University of Cagliari, Cagliari, Italy

    Guido Crisponi & Valeria M. Nurchi

  2. Dipartimento di Citomorfologia, Divisione di Anatomia Patologica, University of Cagliari, Cagliari, Italy

    Gavino Faa

  3. Dipartimento di Chimica, University of Ferrara, Ferrara, Italy

    Maurizio Remelli

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  1. Guido Crisponi
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  2. Valeria M. Nurchi
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  3. Gavino Faa
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  4. Maurizio Remelli
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Correspondence to Guido Crisponi.

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Crisponi, G., Nurchi, V.M., Faa, G. et al. Human diseases related to aluminium overload. Monatsh Chem 142, 331–340 (2011). https://doi.org/10.1007/s00706-011-0474-x

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