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Genomic sequence of an avian paramyxovirus type 1 strain isolated from Muscovy duck (Cairina moschata) in China

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Abstract

The complete sequence of an avian paramyxovirus type 1 (APMV-1) strain, FP1/02, isolated from Muscovy duck in China, was determined. Sequence analysis indicated that the complete genome of strain FP1/02 contained 15,192 nucleotides (nt), following the rule of six. The genome contained an extra 6-nt insertion in the non-coding region of the NP gene when compared with other APMV-1 strains, such as strains La Sota and Beaudette C. The cleavage site of the F protein was 112R-R-Q-K-R↓F117, indicating that the FP1/02 strain was virulent, but the morbidity and mortality varied with the species of duck. Genotypic analysis based on the F gene revealed that APMV-1 FP1/02 was a member of genotype VII. Phylogenetic analysis showed that the FP1/02 strain shared high identity with other APMV-1 strains such as ZJ1, SF02 and NA-1 isolated from geese.

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Acknowledgments

This work was supported by a grant from the National Natural Science Foundation of China (Grant No. 30671564) and the Ministry of Science and Technology of China (Grant No. 2005CB523001).

Conflict of interest

All authors have read and approved the content and have contributed significantly to the work, and none of the authors has any potential financial conflict of interest related to this manuscript.

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Authors and Affiliations

  1. Institute of Animal Husbandry and Veterinary, Fujian Academy of Agricultural Sciences, Fuzhou, 350013, Fujian, People’s Republic of China

    S.-H. Shi, Yu Huang, L.-F. Cheng, G.-H. Fu, Z. Chen, C.-X. Peng, F. Lin & J.-S. Lin

  2. Fujian Animal Diseases Control Technology Development Center, Fuzhou, 350013, Fujian, People’s Republic of China

    S.-H. Shi

  3. Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, 150001, Heilongjiang, People’s Republic of China

    S.-J. Cui & X. Li

  4. Key Laboratory of Zoonosis of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, 100193, People’s Republic of China

    Jing-Liang Su

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  1. S.-H. Shi
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  4. L.-F. Cheng
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Correspondence to Yu Huang or Jing-Liang Su.

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Shi, SH., Huang, Y., Cui, SJ. et al. Genomic sequence of an avian paramyxovirus type 1 strain isolated from Muscovy duck (Cairina moschata) in China. Arch Virol 156, 405–412 (2011). https://doi.org/10.1007/s00705-010-0866-y

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  • DOI: https://doi.org/10.1007/s00705-010-0866-y

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