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Genetic and antigenic typing of rabies virus in Chile

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 Forty-one isolates of rabies virus from insectivorous bats and one from a domestic cat in Chile, were characterized using eight anti-nucleoprotein monoclonal antibodies (N-Mabs) and by nucleotide sequence analysis. Thirty-two isolates were identified as antigenic variant 4 associated with Tadarida brasiliensis bats, twenty-eight were genetically associated with variant Tadarida brasiliensis and four with Lasiurus sp. bats. One isolate was identified as antigenic variant 3 associated with Desmodus rotundus bats, and by genetic analysis was identified as variant Myotis sp. bat. Eight isolates were unrelated to any antigenic variant, and they were identified as a genetic variant associated with Histiotus sp. bats. These antigenic and genetic characterizations may establish epidemiological links between rabies cases and increase the understanding of rabies epidemiology in this country.

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Received January 2, 2002; accepted July 22, 2002

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Yung, V., Favi, M. & Fernández, J. Genetic and antigenic typing of rabies virus in Chile . Arch Virol 147, 2197–2205 (2002). https://doi.org/10.1007/s00705-002-0894-3

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  • DOI: https://doi.org/10.1007/s00705-002-0894-3

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