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Development of a clinical diagnosis support tool to identify patients with lumbar spinal stenosis

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Abstract

No clinical diagnostic support tool can help identify patients with LSS. Simple diagnostic tool may improve the accuracy of the diagnosis of LSS. The aim of this study was to develop a simple clinical diagnostic tool that may help physicians to diagnose LSS in patients with lower leg symptoms. Patients with pain or numbness of the lower legs were prospectively enrolled. The diagnosis of LSS by experienced orthopedic specialists was the outcome measure. Multivariable logistic regression analysis identified factors that predicted LSS; a simple clinical prediction rule was developed by assigning a risk score to each item based on the estimated beta-coefficients. From December 2002 to December 2004, 104 orthopedic physicians from 22 clinics and 50 hospitals evaluated 468 patients. Two items of physical examination, three items of patients' symptom, and five items of physical examination were included in the final scoring system as a result of multiple logistic regression analysis. The sum of the risk scores for each patient ranged from −2 to 16. The Hosmer–Lemeshow statistic was 11.30 (P = 0.1851); the area under the ROC curve was 0.918. The clinical diagnostic support tool had a sensitivity of 92.8% and a specificity of 72.0%. The prevalence of LSS was 6.3% in the bottom quartile of the risk score (−2 to 5) and 99.0% in the top quartile (12 to 16). We developed a simple clinical diagnostic support tool to identify patients with LSS. Further studies are needed to validate this tool in primary care settings.

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References

  1. Amundsen T, Weber H, Lilleas F, Nordal HJ, Abdelnoor M, Magnaes B (1995) Lumbar spinal stenosis. Clinical and radiologic features. Spine 20:1178–1186

    Article  PubMed  CAS  Google Scholar 

  2. Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, et al (1988) The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 31:315–324

    Article  PubMed  CAS  Google Scholar 

  3. Beattie PF, Meyers SP, Stratford P, Millard RW, Hollenberg GM (2000) Associations between patient report of symptoms and anatomic impairment visible on lumbar magnetic resonance imaging. Spine 25:819–828

    Article  PubMed  CAS  Google Scholar 

  4. Boden SD, Davis DO, Dina TS, Patronas NJ, Wiesel SW (1990) Abnormal magnetic-resonance scans of the lumbar spine in asymptomatic subjects. A prospective investigation. J Bone Joint Surg Am 72:403–408

    PubMed  CAS  Google Scholar 

  5. Chalmers I (1990) Underreporting research is scientific misconduct. Jama 263:1405–1408

    Article  PubMed  CAS  Google Scholar 

  6. Collins TC, Suarez-Almazor M, Peterson NJ (2006) An absent pulse is not sensitive for the early detection of peripheral arterial disease. Fam Med 38:38–42

    PubMed  Google Scholar 

  7. Coulier B, Devyver B, Ghosez JP (2003) Severe underestimation of lumbar spinal stenosis by supine imaging. Clin Radiol 58:167–169

    Article  PubMed  CAS  Google Scholar 

  8. de Graaf I, Prak A, Bierma-Zeinstra S, Thomas S, Peul W, Koes B (2006) Diagnosis of lumbar spinal stenosis: a systematic review of the accuracy of diagnostic tests. Spine 31:1168–1176

    Article  PubMed  Google Scholar 

  9. Feinstein AR (1985) Clinical epidemiology: the architecture of clinical research. WB Saunders, Philadelphia

    Google Scholar 

  10. Goldman SM, Funk JD, Christensen VM (1997) Spinal stenosis. A common cause of podiatric symptoms. J Am Podiatr Med Assoc 87:117–124

    PubMed  CAS  Google Scholar 

  11. Goldman SM (2004) Diabetic peripheral neuropathy and spinal stenosis: prevalence of overlap and misdiagnosis. An introductory report. Diabet Med 21:394–396

    Article  PubMed  CAS  Google Scholar 

  12. Jonsson A, Rydberg T, Sterner G, Melander A (1998) Pharmacokinetics of glibenclamide and its metabolites in diabetic patients with impaired renal function. Eur J Clin Pharmacol 53:429–435

    Article  PubMed  CAS  Google Scholar 

  13. Katz JN, Liang MH (1991) Classification criteria revisited. Arthritis Rheum 34:1228–1230

    Article  PubMed  CAS  Google Scholar 

  14. Laupacis A, Sekar N, Stiell IG (1997) Clinical prediction rules. A review and suggested modifications of methodological standards. Jama 277:488–494

    Article  PubMed  CAS  Google Scholar 

  15. Lawrence JS (1969) Disc degeneration. Its frequency and relationship to symptoms. Ann Rheum Dis 28:121–138

    Article  PubMed  CAS  Google Scholar 

  16. McGinn TG, Guyatt GH, Wyer PC, Naylor CD, Stiell IG, Richardson WS (2000) Users’ guides to the medical literature: XXII: how to use articles about clinical decision rules. Evidence-Based Medicine Working Group. Jama 284:79–84

    Article  PubMed  CAS  Google Scholar 

  17. Powell MC, Wilson M, Szypryt P, Symonds EM, Worthington BS (1986) Prevalence of lumbar disc degeneration observed by magnetic resonance in symptomless women. Lancet 2:1366–1367

    Article  PubMed  CAS  Google Scholar 

  18. Spengler DM(1987) Degenerative stenosis of the lumbar spine. J Bone Joint Surg Am 69:305–308

    PubMed  CAS  Google Scholar 

  19. Stafira JS, Sonnad JR, Yuh WT, Huard DR, Acker RE, Nguyen DL, Maley JE, Ramji FG, Li WB, Loftus CM (2003) Qualitative assessment of cervical spinal stenosis: observer variability on CT and MR images. AJNR Am J Neuroradiol 24:766–769

    PubMed  Google Scholar 

  20. Stucki G, Liang MH, Lipson SJ, Fossel AH, Katz JN (1994) Contribution of neuromuscular impairment to physical functional status in patients with lumbar spinal stenosis. J Rheumatol 21:1338–1343

    PubMed  CAS  Google Scholar 

  21. Waddell G, Somerville D, Henderson I, Newton M (1992) Objective clinical evaluation of physical impairment in chronic low back pain. Spine 17:617–628

    Article  PubMed  CAS  Google Scholar 

  22. Wiesel SW, Tsourmas N, Feffer HL, Citrin CM, Patronas N (1984) A study of computer-assisted tomography. I. The incidence of positive CAT scans in an asymptomatic group of patients. Spine 9:549–551

    Article  PubMed  CAS  Google Scholar 

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Correspondence to Shinichi Konno.

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Konno, S., Hayashino, Y., Fukuhara, S. et al. Development of a clinical diagnosis support tool to identify patients with lumbar spinal stenosis. Eur Spine J 16, 1951–1957 (2007). https://doi.org/10.1007/s00586-007-0402-2

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  • DOI: https://doi.org/10.1007/s00586-007-0402-2

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