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Changes in behavior as an early symptom of renovascular hypertension in children

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Abstract

Renovascular hypertension in children is usually asymptomatic and diagnosed incidentally. Behavioral changes have not yet been well recognized as a part of the clinical spectrum of renovascular disease in children. We surveyed all children diagnosed with renovascular hypertension in our institute over a 15-year period. Eleven children were identified, of whom five (45%) had abnormal behavior, which had preceded the diagnosis of hypertension by 3–12 months. The symptoms included restlessness, sleep disturbances, temper tantrums, hyperactivity, aggressive behavior and attention deficit. In three children all behavioral symptoms disappeared following blood pressure normalization, and, in the other two a significant improvement was noted. It was concluded that behavioral symptoms may be a common and early manifestation of renovascular hypertension. Awareness of this association may bring about earlier diagnosis of the disease and prevent end-organ damage as well as unnecessary investigations for behavioral abnormalities.

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Authors and Affiliations

  1. Pediatric Nephrology Institute, Schneider’s Children Medical Center of Israel, Petah-Tiqva, 49202, Israel

    Irit Krause, Roxana Cleper, Yael Kovalski & Miriam Davidovits

  2. Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel

    Irit Krause, Roxana Cleper, Yael Kovalski & Miriam Davidovits

  3. Children Medical Center, Ramla, Israel

    Yael Kovalski

  4. Department of Pediatrics, Kaplan Medical Center, Rehovot, Israel

    Levana Sinai

  5. Faculty of Medicine, Hebrew University, Jerusalem, Israel

    Levana Sinai

Authors
  1. Irit Krause
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  2. Roxana Cleper
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  3. Yael Kovalski
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  4. Levana Sinai
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  5. Miriam Davidovits
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Correspondence to Irit Krause.

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Krause, I., Cleper, R., Kovalski, Y. et al. Changes in behavior as an early symptom of renovascular hypertension in children. Pediatr Nephrol 24, 2271–2274 (2009). https://doi.org/10.1007/s00467-009-1205-y

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  • DOI: https://doi.org/10.1007/s00467-009-1205-y

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